DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment twz and AgaP_AGAP007046

DIOPT Version :9

Sequence 1:	NP_001246449.1	Gene:	twz / 37456	FlyBaseID:	FBgn0034636	Length:	367	Species:	Drosophila melanogaster
Sequence 2:	XP_308716.2	Gene:	AgaP_AGAP007046 / 1270054	VectorBaseID:	AGAP007046	Length:	550	Species:	Anopheles gambiae

Alignment Length:	214	Identity:	50/214 - (23%)
Similarity:	72/214 - (33%)	Gaps:	86/214 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 AAAAAVGGASSAGASSYLHGNHKPITGIPCVAAASRYTAPVH------------IDVGGTIYTSS 149
            |.|||:|..              ||...|..|      .||.            |:|.|..:.:.
Mosquito    11 ARAAAIGWV--------------PIASHPLPA------PPVFKDRLRSEDEKLIINVSGRRFETW 55

  Fly   150 LETLTKYPESKLAKLFNGQIPIVLDSLKQHYFIDRDGGMFRHILNFMRNSRLLIAEDFPDLELLL 214
            ..|:.|||::.|.   :.:.....|...:.||.|||..:||||||:.|..:|    .:|..|.||
Mosquito    56 RTTVEKYPDTLLG---SNERDFFYDEDSKEYFFDRDPDIFRHILNYYRTGKL----HYPRHECLL 113

  Fly   215 ---EEARYYEVEPMIKQLESMRKDRVRNGNYLVAPPTPPARHIKTSPRTSASPECNYEVVALHIS 276
               ||..::.:.|                                    ....:|.||
Mosquito   114 SYDEELAFFGIMP------------------------------------DVIGDCCYE------- 135

  Fly   277 PDLGERIMLSAERALLDEL 295
             |..:|...:|||.:.|:|
Mosquito   136 -DYRDRKRENAERLMDDKL 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
twz	NP_001246449.1	BTB_POZ_KCTD1-like	137..230	CDD:349670	30/107 (28%)
AgaP_AGAP007046	XP_308716.2	BTB_POZ_Shal-like	6..144	CDD:349727	45/203 (22%)
		Ion_trans	184..415	CDD:395416
		DUF3399	459..543	CDD:403174
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910