Protein Alignment twz and kctd1

DIOPT Version :10

• Sequence 1: NP_001246449.1
• Gene: twz / 37456
• FlyBaseID: FBgn0034636
• Length: 367
• Species: Drosophila melanogaster
• Sequence 2: XP_012820753.2
• Gene: kctd1 / 100486970
• XenbaseID: XB-GENE-6076050
• Length: 840
• Species: Xenopus tropicalis
• Alignment Length: 346
• Identity: 146/346 - (42%)
• Similarity: 194/346 - (56%)
• Gaps: 59/346 - (17%)

  Fly    47 SSTGRIYARSDIKISSSP---TVSP--------TISNSSSPTPTPPASSSVTPLGLPGAVAAAAA 100
            :|...|||..|:....||   .:.|        .:|..|.|.|:.|.::.       ..|.||:.
 Frog   509 NSAHSIYASGDMGSPPSPKRLCIRPADPSDCVHVVSVKSDPQPSCPETNG-------HMVLAASP 566

  Fly   101 AVGGASSAGASSYLHGN-HKPI-----------TGIPCVAAASRYTAPVHIDVGGTIYTSSLETL 153
            ||...|..........| .:|:           .|||..|..::..|||||||||.:|||||.||
 Frog   567 AVTSPSVMSPVQDTRPNMSRPLITRSPASPLSNQGIPTPAQLTKSNAPVHIDVGGHMYTSSLATL 631

  Fly   154 TKYPESKLAKLFNGQIPIVLDSLKQHYFIDRDGGMFRHILNFMRNSRLLIAEDFPDLELLLEEAR 218
            ||||:|::.:||:|..|||||||||||||||||.|||:||||:|.|:|||::||.|..||.|||:
 Frog   632 TKYPDSRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFLRTSKLLISDDFKDYSLLYEEAK 696

  Fly   219 YYEVEPMIKQLESMRKDRVRNGNYLVAPPTPPARHIKTSPRTSASPECNYEVVALHISPDLGERI 283
            |::::||:.:||..::|                   |.:.|.|...||    :.:.::|||||||
 Frog   697 YFQLQPMLLELERWKQD-------------------KEAGRFSRPCEC----LVVRVAPDLGERI 738

  Fly   284 MLSAERALLDELFPEASQATQSSRSGVSWNQGDWGQIIRFPLNGYCKLNSVQVLTRLLNAGFTIE 348
            .||.:::|::|:|||......:| ....||. |...:|||||||||.|||||||.||.:.||.|.
 Frog   739 TLSGDKSLIEEVFPEIGDVMCNS-VNAGWNH-DSTHVIRFPLNGYCHLNSVQVLERLQHRGFEIV 801

  Fly   349 ASVGG----QQFSEYLLARRV 365
            .|.||    .|||||:|.|.:
 Frog   802 GSCGGGVDSSQFSEYVLRREL 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
twz	NP_001246449.1	BTB_POZ_KCTD1-like	137..230	CDD:349670	62/92 (67%)
kctd1	XP_012820753.2	DUF3504	270..432	CDD:463430
		BTB_POZ_KCTD1	611..715	CDD:349695	67/122 (55%)