| Sequence 1: | NP_476759.1 | Gene: | Egfr / 37455 | FlyBaseID: | FBgn0003731 | Length: | 1426 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001005861.1 | Gene: | RYK / 6259 | HGNCID: | 10481 | Length: | 610 | Species: | Homo sapiens |
| Alignment Length: | 494 | Identity: | 135/494 - (27%) |
|---|---|---|---|
| Similarity: | 215/494 - (43%) | Gaps: | 120/494 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 762 HYKRREQCETECPADHYTDEEQRECFQCHPECNGCTGPGADDCKSCRNFKLFDANETGPYVNSTM 826
Fly 827 FNCTSKCPLEMRHVNYQYTAIGPYCAASPPRSSKITANLDVNMIFIITGAVLVPTICILCVVTYI 891
Fly 892 CRQKQKAKKETVKMTMALSGCEDSEP-------LR---PSN---IGANL--CKLRIVKDAELR-- 939
Fly 940 -----KG---------------GVLGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAE-SSE 983
Fly 984 EFLREAYIMASVEHVNLLKLLAVCM--SSQMMLITQLMPLGCLLDYVR-------NNRDKIGSKA 1039
Fly 1040 LLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQTPSLVKITDFGLAK-LLSSDSNEYKAAGG--K 1101
Fly 1102 MPIKWLALECIRNRVFTSKSDVWAFGVTIWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICS 1166
Fly 1167 LDIYCTLLSCWHLDAAMRPTFKQLTTVFAEFARDPGRYL 1205 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Egfr | NP_476759.1 | Recep_L_domain | 419..547 | CDD:279382 | |
| GF_recep_IV | 572..684 | CDD:291509 | |||
| FU | 573..>606 | CDD:238021 | |||
| FU | 617..659 | CDD:214589 | |||
| FU | 662..716 | CDD:214589 | |||
| FU | 739..786 | CDD:238021 | 6/23 (26%) | ||
| FU | 784..834 | CDD:214589 | 6/49 (12%) | ||
| PTKc_EGFR_like | 930..1208 | CDD:270648 | 105/311 (34%) | ||
| STYKc | 938..1194 | CDD:214568 | 97/290 (33%) | ||
| Recep_L_domain | 128..239 | CDD:279382 | |||
| Furin-like | 253..401 | CDD:279142 | |||
| FU | 255..292 | CDD:214589 | |||
| FU | 302..345 | CDD:238021 | |||
| RYK | NP_001005861.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..20 | ||
| WIF | 63..196 | CDD:128745 | 4/16 (25%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 266..290 | 5/25 (20%) | |||
| PTK_Ryk | 326..606 | CDD:270639 | 95/282 (34%) | ||
| Pkinase_Tyr | 333..599 | CDD:285015 | 93/268 (35%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1025 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||