DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Egfr and LOC108191339

DIOPT Version :9

Sequence 1:	NP_476759.1	Gene:	Egfr / 37455	FlyBaseID:	FBgn0003731	Length:	1426	Species:	Drosophila melanogaster
Sequence 2:	XP_017213329.1	Gene:	LOC108191339 / 108191339	-ID:	-	Length:	178	Species:	Danio rerio

Alignment Length:	190	Identity:	80/190 - (42%)
Similarity:	112/190 - (58%)	Gaps:	32/190 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1102 MPIKWLALECIRNRVFTSKSDVWAFGVTIWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICS 1166
            |||||:|||||..|.||.:||||::|||||||:|||.:|::.||.::||||:|.|.:|.||.||:
Zfish     1 MPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICT 65

  Fly  1167 LDIYCTLLSCWHLDAAMRPTFKQLTTVFAEFARDPGRYLAIPGDKFTRLPAYTSQ-------DEK 1224
            :|:|..::.||.:||..||.||:|...|:..||||.|||.|.||...:||:....       ||:
Zfish    66 IDVYMVMVKCWMIDADSRPRFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQSLLDEE 130

  Fly  1225 DLIRKLAPTTDGSEAIAEPDDYLQPKAAPGPSHRTDCTDEIPKL---NRYCKDPSNKNSS 1281
            :|           |.:.:.::||.|:|.           .||.|   .|...||:..::|
Zfish   131 EL-----------EDLMDAEEYLVPQAY-----------SIPPLAYTTRSRMDPNRVSAS 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Egfr	NP_476759.1	Recep_L_domain	419..547	CDD:279382
		GF_recep_IV	572..684	CDD:291509
		FU	573..>606	CDD:238021
		FU	617..659	CDD:214589
		FU	662..716	CDD:214589
		FU	739..786	CDD:238021
		FU	784..834	CDD:214589
		PTKc_EGFR_like	930..1208	CDD:270648	60/105 (57%)
		STYKc	938..1194	CDD:214568	52/91 (57%)
		Recep_L_domain	128..239	CDD:279382
		Furin-like	253..401	CDD:279142
		FU	255..292	CDD:214589
		FU	302..345	CDD:238021
LOC108191339	XP_017213329.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D51516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010