Protein Alignment CG30283 and Cfd

DIOPT Version :10

• Sequence 1: NP_611587.2
• Gene: CG30283 / 37454
• FlyBaseID: FBgn0260477
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_001071110.1
• Gene: Cfd / 54249
• RGDID: 2498
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 280
• Identity: 82/280 - (29%)
• Similarity: 134/280 - (47%)
• Gaps: 43/280 - (15%)

  Fly     3 NTKIFVVVVLLAASSVVVLGSESGSFLEHPCGTVPISQFKILGGHNAPVASAPWMAMVMGEGGFH 67
            ::.:::|.:::..::|.|         ..|.|       :||||..|...:.|:||.|...|...
  Rat     2 HSSVYLVALVVLEAAVCV---------AQPRG-------RILGGQEAMAHARPYMASVQVNGTHV 50

  Fly    68 CGGTLITNRFVLTSAHC---IANGE-LKVRLG---VLEREAEAQKFAVDAMFVHTDYYFD--QHD 123
            |||||:..::||::|||   :...| ::|.||   :...|.....:.|.::.:|.....|  :.|
  Rat    51 CGGTLVDEQWVLSAAHCMDGVTKDEVVQVLLGAHSLSSPEPYKHLYDVQSVVLHPGSRPDSVEDD 115

  Fly   124 LALLRLAKRVHYSDNISPICLLLDPLVKNIDEHIVKFRTY----GWG-KTESRSSSRMLQKTSLF 183
            |.|.:|:.......::.|:     ||.:  ::..||..|.    ||| .|.:.....:||:.::.
  Rat   116 LMLFKLSHNASLGPHVRPL-----PLQR--EDREVKPGTLCDVAGWGVVTHAGRRPDVLQQLTVS 173

  Fly   184 NLHRSEC-AKQYPHQQINRNHICAESANANTCNGDSGGPLTAIVTYDHVQMVFQFGVTSFGHADC 247
            .:.|:.| .:.|....|.:|.:||||...:||.|||||||   |..|.|:.|..:|....|:.
  Rat   174 IMDRNTCNLRTYHDGAITKNMMCAESNRRDTCRGDSGGPL---VCGDAVEAVVTWGSRVCGNR-- 233

  Fly   248 SKATVFTNVMTHLDWIVNTV 267
            .|..|||.|.|::.||.|.:
  Rat   234 RKPGVFTRVATYVPWIENVL 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30283	NP_611587.2	Tryp_SPc	42..263	CDD:214473	74/235 (31%)
Cfd	NP_001071110.1	Tryp_SPc	26..252	CDD:238113	76/237 (32%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		1/3 (33%)