Protein Alignment CG30283 and GZMK

DIOPT Version :10

• Sequence 1: NP_611587.2
• Gene: CG30283 / 37454
• FlyBaseID: FBgn0260477
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_002095.1
• Gene: GZMK / 3003
• HGNCID: 4711
• Length: 264
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 73/269 - (27%)
• Similarity: 116/269 - (43%)
• Gaps: 60/269 - (22%)

  Fly    26 GSFLEHPCGTVPISQFKILGGHNAPVASAPWMAMVMGEGGFH-CGGTLITNRFVLTSAHC---IA 86
            |:::.|.|     ...:|:||......|.|:||.:. .||.| |||.||..::|||:|||   ..
Human    15 GAYMTHVC-----FNMEIIGGKEVSPHSRPFMASIQ-YGGHHVCGGVLIDPQWVLTAAHCQYRFT 73

  Fly    87 NGEL-KVRLG---VLEREAEAQKFAVDAMFVHTDYYFD--QHDLALLRLAKRVHYSDNISPICLL 145
            .|:. .|.||   :.:.||..|...:......:....|  .:|:.|::|......:.::..:
Human    74 KGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKML--- 135

  Fly   146 LDPLVKNIDEHI---------VKFRTYGWGKT--ESRSSSRMLQKTSLFNLHRSECAKQYPHQQ- 198
                      ||         .|.:..|||.|  :|...|..|::.::..|.|..|..|..:..
Human   136 ----------HIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGD 190

  Fly   199 --INRNHICAESANA--NTCNGDSGGPLTAIVTYDHVQMVFQFGVTSFGHADCSKAT---VFTNV 256
              |.::.:||..|..  ::|.|||||||..       :.||. .:.|.|| :|..||   ::| :
Human   191 PFITKDMVCAGDAKGQKDSCKGDSGGPLIC-------KGVFH-AIVSGGH-ECGVATKPGIYT-L 245

  Fly   257 MT--HLDWI 263
            :|  :..||
Human   246 LTKKYQTWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30283	NP_611587.2	Tryp_SPc	42..263	CDD:214473	68/251 (27%)
GZMK	NP_002095.1	Tryp_SPc	27..257	CDD:238113	70/252 (28%)