DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30283 and Habp2

DIOPT Version :9

Sequence 1:	NP_611587.2	Gene:	CG30283 / 37454	FlyBaseID:	FBgn0260477	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001001505.2	Gene:	Habp2 / 292126	RGDID:	1302979	Length:	558	Species:	Rattus norvegicus

Alignment Length:	285	Identity:	88/285 - (30%)
Similarity:	133/285 - (46%)	Gaps:	49/285 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LGSESGSFLEHP----CGTVPISQF---KILGGHNAPVASAPWMAMV---------MGEGGFHCG 69
            |||.....:|.|    ||...:::.   :|.||..:.....||...:         |.:|.| ||
  Rat   283 LGSLQEPVMELPGFDSCGKTEMTEHAVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHF-CG 346

  Fly    70 GTLITNRFVLTSAHC--IANGELKVRLG---VLEREAEAQKFAVDAMFVHTDY----YFDQHDLA 125
            |:||...:|||:|||  ::...|||.||   :.:.|:..|.|.|:.:..::.|    ....:|:|
  Rat   347 GSLIHPCWVLTAAHCTDMSTKHLKVVLGDQDLKKTESHEQTFRVEKILKYSQYNERDEIPHNDIA 411

  Fly   126 LLRLAKRV--H---YSDNISPICLLLDPLVKNIDEHIVKFRTYGWGKTESRSSSRMLQKTSLFNL 185
            ||:| |.|  |   .|..:..:||..||.....:.||     .|||.||:...||.|....:..:
  Rat   412 LLKL-KPVGGHCALESKYVKTVCLPSDPFPSGTECHI-----SGWGVTETGEGSRQLLDAKVKLI 470

  Fly   186 HRSEC-AKQYPHQQINRNHICA---ESANANTCNGDSGGPLTAIV--TYDHVQMVFQFGVTSFGH 244
            ..:.| ::|.....|:.:.|||   :...::||.||||||||...  ||      :.:|:.|:|.
  Rat   471 ANALCNSRQLYDHTIDDSMICAGNLQKPGSDTCQGDSGGPLTCEKDGTY------YVYGIVSWGQ 529

  Fly   245 ADCSKATVFTNVMTHLDWIVNTVRR 269
            ....|..|:|.|...|:||..|:.:
  Rat   530 ECGKKPGVYTQVTKFLNWIKTTMHK 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30283	NP_611587.2	Tryp_SPc	42..263	CDD:214473	78/249 (31%)
CG30283	NP_611587.2	Tryp_SPc	43..266	CDD:238113	80/251 (32%)
Habp2	NP_001001505.2	EGF_CA	71..107	CDD:238011
		KR	191..275	CDD:238056
		Tryp_SPc	312..551	CDD:238113	80/251 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336756
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930