DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30283 and Mst1

DIOPT Version :9

Sequence 1:	NP_611587.2	Gene:	CG30283 / 37454	FlyBaseID:	FBgn0260477	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_032269.3	Gene:	Mst1 / 15235	MGIID:	96080	Length:	716	Species:	Mus musculus

Alignment Length:	274	Identity:	73/274 - (26%)
Similarity:	119/274 - (43%)	Gaps:	50/274 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 SFLEHP-------CG--TVPISQFKILGGHNAPVASAPWMAMVMGEGGFH-CGGTLITNRFVLTS 81
            |.|:.|       ||  ....::.:::|||   ..::||...:....|.| |||:|:..::|||:
Mouse   464 SILDPPDQVVFEKCGKRVDKSNKLRVVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWVLTA 525

  Fly    82 AHCIANGE-----LKVRLGVLER-----EAEAQKFAVDAMFVHTDYYFDQHDLALLRLAKRVHYS 136
            ..||.:..     .:|.||.:.:     ||..|:..|.......    ....|.||:|.:.|..:
Mouse   526 RQCIWSCHEPLTGYEVWLGTINQNPQPGEANLQRVPVAKAVCGP----AGSQLVLLKLERPVILN 586

  Fly   137 DNISPICLLLDPLVKNIDEHIV----KFRTYGWGKTESRSSSRMLQKTSLFNLHRSECAKQYPHQ 197
            .:::.||  |.|     ::::|    |....|||::...|::.:|...|:..:...||..:| ..
Mouse   587 HHVALIC--LPP-----EQYVVPPGTKCEIAGWGESIGTSNNTVLHVASMNVISNQECNTKY-RG 643

  Fly   198 QINRNHICAES--ANANTCNGDSGGPLTAIVTYDHVQMVFQFGVTSFGHADCSK---ATVFTNVM 257
            .|..:.||.:.  .....|.||.||||..   |.|...|.| |:. ..:..|::   ..:||.|.
Mouse   644 HIQESEICTQGLVVPVGACEGDYGGPLAC---YTHDCWVLQ-GLI-IPNRVCARPRWPAIFTRVS 703

  Fly   258 THLDWIVNTVRRAE 271
            ..:||| |.|.:.|
Mouse   704 VFVDWI-NKVMQLE 716

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30283	NP_611587.2	Tryp_SPc	42..263	CDD:214473	63/240 (26%)
CG30283	NP_611587.2	Tryp_SPc	43..266	CDD:238113	65/242 (27%)
Mst1	NP_032269.3	PAN_1	25..96	CDD:278453
		KR	108..188	CDD:214527
		KR	191..269	CDD:214527
		KR	291..372	CDD:214527
		KR	377..459	CDD:214527
		Tryp_SPc	488..709	CDD:214473	63/240 (26%)
		Tryp_SPc	489..712	CDD:238113	66/243 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833173
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930