DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30283 and CG43742

DIOPT Version :9

Sequence 1:	NP_611587.2	Gene:	CG30283 / 37454	FlyBaseID:	FBgn0260477	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001261130.1	Gene:	CG43742 / 14462622	FlyBaseID:	FBgn0263999	Length:	474	Species:	Drosophila melanogaster

Alignment Length:	278	Identity:	92/278 - (33%)
Similarity:	144/278 - (51%)	Gaps:	40/278 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VLLAASSVVVLGSESGSFLEHPCGTVPISQFKILGGHNAPVASAPWMAMVMGEGGFHCGGTLITN 75
            :||.|  ||:..:.....|:..| .|.|: :::..||.|  .::.:||.:.....|.|||:||..
  Fly     7 LLLVA--VVIYQNAFAQLLDENC-KVKIT-YRVANGHTA--ITSQFMAALYNNSEFFCGGSLIHK 65

  Fly    76 RFVLTSAHCIAN-GELKVRLG-------------VLEREAEAQKFAVDAMFVHTDYYFD--QHDL 124
            ::|||:|||:.: .|:.|.||             ||...|:        :.:|.:::.:  .:|:
  Fly    66 QYVLTAAHCVRDLDEVTVHLGENNRSCPIPVCKHVLRLNAK--------VILHPNFHGNIFLNDI 122

  Fly   125 ALLRLAKRVHYSDNISPICLLLDPLVKNIDEHIVKFRTYGWGKTESRSSSRMLQKTSLFNLHRSE 189
            |||||.:.|.:..:|.|||::||..|.:.:::  .|..|||||||..:.|.:|....|..|.:|.
  Fly   123 ALLRLEREVIFEAHIRPICIILDEDVTSNNQN--NFTAYGWGKTEHGNISDVLSFIDLVRLPKSM 185

  Fly   190 CAKQYPHQQINRNHICAESANANTCNGDSGGPLTAIVTYDHVQMVFQFGVTSFGHADCSKA-TVF 253
            |     :|.||.  |||.|.:.:||..||||||.....:........||:||:|.|:||.. .|:
  Fly   186 C-----YQNINT--ICAGSTSGDTCESDSGGPLIGNFVHRGKSRDILFGITSYGDAECSGLFGVY 243

  Fly   254 TNVMTHLDWIVNTVRRAE 271
            |:|..:..||.:.|..:|
  Fly   244 TDVNAYKSWIASVVLESE 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30283	NP_611587.2	Tryp_SPc	42..263	CDD:214473	79/237 (33%)
CG30283	NP_611587.2	Tryp_SPc	43..266	CDD:238113	81/239 (34%)
CG43742	NP_001261130.1	Tryp_SPc	34..253	CDD:214473	79/237 (33%)
		Tryp_SPc	35..256	CDD:238113	81/239 (34%)
		Tryp_SPc	273..467	CDD:214473
		Tryp_SPc	273..>368	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.050