DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10494 and Zscan20

DIOPT Version :10

Sequence 1:NP_726079.1 Gene:CG10494 / 37453 FlyBaseID:FBgn0034634 Length:523 Species:Drosophila melanogaster
Sequence 2:NP_808426.2 Gene:Zscan20 / 269585 MGIID:2679268 Length:1030 Species:Mus musculus


Alignment Length:702 Identity:133/702 - (18%)
Similarity:218/702 - (31%) Gaps:256/702 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 CKWTSAK------------VETFLEII-HQLKLQAALRRPRSNAKVFRMVSREMARRNCPKSPKH 96
            |:|...:            :|.||.|: .:::.....|.|.|..:...:|.              
Mouse    71 CRWLRPELRLKEQILELLVLEQFLSILPREVQTWVQARHPESGEEAVALVE-------------- 121

  Fly    97 LRVKFHQMRRQYARARNG----GEPFEHFEAVHELM-----------QGE-----------DVSD 135
               .:|  |..:|..:.|    .|....||||.|..           :|:           |:|.
Mouse   122 ---DWH--REAWAAGQQGLELCSEDSRSFEAVQEFQRFQLQPVTHGSEGQPRKQWVENARPDLSK 181

  Fly   136 LDEEALESDSDM----------------------------------EADEDQSG----------- 155
            :..|:|:..:.:                                  |..:|.:|           
Mouse   182 MPPESLKESAVLTPQAPTVPKMASIGDWEVAGKSQETPSPSRQAKKEPCQDPAGGDRGDSACLGV 246

  Fly   156 ---------------------MISETEG---DDALD-ASGSSVNIVAR---------CKWAEGEV 186
                                 :|:...|   ||:|| |....|..||:         |:|  |..
Mouse   247 PASKPSATSQQEQGPEIWGLSLINSGNGSAADDSLDSAQDKPVQAVAQADSRAWGEPCQW--GAE 309

  Fly   187 DLLLDLIH-----TLGLRAALLQK----------RNAKVFKLLSKEMAKRNCHKGAEKLRIKFQQ 236
            |:.:..:|     |....|.|.:.          :|.:|::.:::.:..|...:..|:.|.:.:.
Mouse   310 DMKVSGVHWGYEETKTFLAILSESPFSEKLQTCHQNRQVYRAIAERLRARGFLRTLEQCRYRVKN 374

  Fly   237 LRRLYNKVKN----GTGKTFEHFEAMRLVLDPTEEEAAADAEAEAHLSSASDSDFNDSDEEEGD- 296
            |.|.|.|.||    ||...:|..||:..........:....||.| |....|||....|::||. 
Mouse   375 LLRNYRKAKNSHPPGTCPFYEELEALVRARTAIRRTSGGPGEAVA-LPRLGDSDTEMDDQDEGSW 438

  Fly   297 --------------------------------ASQRSGAHFWTDEEVDSFLLIIRDNGFFRALDG 329
                                            .|:.:|.| |..||...||.|:.::.|...| .
Mouse   439 EPEETVEDCSGSGLAAEESLQGPRIAGGPALLQSRIAGVH-WGFEETKVFLAILSESPFAEKL-R 501

  Fly   330 SRKRNFQTLVHISNILAKQDIKRTPHQLRNKLRLLCKRHREAKE-------------HGLDNVRI 381
            :..:|.|....|:..|......||..|.|.:.:.|.:.:|:||.             ..|...|.
Mouse   502 TCHQNSQIYRAIAERLRALGFLRTLEQCRYRFKNLLRSYRKAKSSCPPGTCPFYEEMDSLMRART 566

  Fly   382 LPRHFELFDELIQAPRENRESAIS------------RLIRISKPSFLKPPGKPSVPLESDSDNSS 434
            :.|..|:..|....|...:.|..:            ..:|:..|.  ..|......|:.:.::..
Mouse   567 VIRAVEMVGEATGLPGSGQSSTEADDQEAWGEMEDEDAVRLLTPD--SQPADAGFELKREEEDQI 629

  Fly   435 STCDLL------------RAAAD----SEDYVDAIEME-----AEPTPIEALTAIIEGQKQLLAQ 478
            |..|:|            :|...    .||:|:..|.|     .|.:..|.|..:|:.|...|.:
Mouse   630 SEQDVLGDLPGALSRYTTKAVCQPCDWGEDHVNGNEGEWRNTWEECSSEEDLEKLIDHQGLYLTE 694

  Fly   479 ----IKTTNESFLRQ------QR----EQQHQFLEQVSELMHRDREETLRRI 516
                ..|..:||.|:      ||    |:.::.|........|....|.:||
Mouse   695 KPYGCDTRAKSFSRKVHFFAPQRTHSSEKPYKCLGSGKSFSDRANLSTHQRI 746

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10494NP_726079.1 Myb_DNA-bind_4 44..123 CDD:463994 16/94 (17%)
Myb_DNA-bind_4 178..257 CDD:463994 22/106 (21%)
Myb_DNA-bind_4 304..391 CDD:463994 25/99 (25%)
Zscan20NP_808426.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 22..42
SCAN 41..126 CDD:460417 11/73 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 178..201 4/22 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 213..285 9/71 (13%)
Myb_DNA-bind_4 315..396 CDD:463994 17/80 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 411..441 10/30 (33%)
Myb_DNA-bind_4 476..557 CDD:463994 22/82 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 578..600 2/21 (10%)
COG5048 686..1020 CDD:227381 14/61 (23%)
C2H2 Zn finger 727..747 CDD:275368 5/20 (25%)
C2H2 Zn finger 755..775 CDD:275368
C2H2 Zn finger 783..803 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 801..820
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 828..850
C2H2 Zn finger 864..884 CDD:275368
C2H2 Zn finger 892..912 CDD:275368
C2H2 Zn finger 920..940 CDD:275368
C2H2 Zn finger 948..968 CDD:275368
C2H2 Zn finger 976..996 CDD:275368
C2H2 Zn finger 1004..1024 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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