Protein Alignment MESK2 and ndrg4

DIOPT Version :9

• Sequence 1: NP_995914.1
• Gene: MESK2 / 37451
• FlyBaseID: FBgn0043070
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_005163134.1
• Gene: ndrg4 / 692305
• ZFINID: ZDB-GENE-060512-226
• Length: 458
• Species: Danio rerio
• Alignment Length: 437
• Identity: 149/437 - (34%)
• Similarity: 202/437 - (46%)
• Gaps: 73/437 - (16%)

  Fly     1 MPSA--PTHTAE--------EAHLLGTMPVDPMDDIELRSVQLQFPNARGSILEACE-------- 47
            :|||  |..||.        ..|.||         :..|.....||       |.||
Zfish    64 LPSATPPPPTARPPKRWHAIAQHWLG---------LTRRRTSGYFP-------ENCETFVATGDW 112

  Fly    48 -QRRVPTDKGDVHVAIQGDTA--KPAIITYHDLGLNYATSFAGFFNFPVMRGLLENFCVYHVTAP 109
             :..:.|..|.:||.|:|...  ||||:||||:|||:...|..||....|..:.::|.|.||.||
Zfish   113 KEHDIETPYGMLHVVIRGAPKGNKPAILTYHDVGLNHKLCFNSFFQNEDMLEITKHFVVCHVDAP 177

  Fly   110 GQEEGAPTLPEDYVYPTMDDLAAQLLFVLSHFGLKSVIGFGVGAGANILARFAHAHPDKVGALCL 174
            ||..|||.:|:.|.|||||.||..|..|:.|||.||::|.||||||.|||:||...||.|..|.|
Zfish   178 GQHIGAPQMPQGYQYPTMDQLAGMLPSVVQHFGFKSIVGIGVGAGAYILAKFALIFPDLVEGLVL 242

  Fly   175 INCVSTQSGWIEWGYQSFNARFLRTKGMTQGVIDYLMWHHFGRNPEERNHDLVQMYKQHFERGVN 239
            :|......|||:|.       ..:..|:|..:.|.::.|.|.:.....|.::||.|:|.....:|
Zfish   243 LNIDPNGKGWIDWA-------ATKLSGLTSTLPDTVLTHLFSQEELMSNTEVVQNYRQQINNTIN 300

  Fly   240 PTNLAMLINAYIHRNDLHLARTPPGTPGSETAATTLKMPVINITGSLSPHVDDTVTFNGRLDPTN 304
            ..||.:..|.|..|.||.:.|:     ||...|.||:.||:.:.|..:|..:..|..|.:|||||
Zfish   301 QFNLQLFWNMYNSRRDLEMNRS-----GSVINAKTLRCPVMLVVGDNAPAEEGVVECNSKLDPTN 360

  Fly   305 SSWMKISDCALVLE-EQPAKLAEAFRLFLQGEGYATPLSTPASSPCGTKYHTYSSIFFANFREQQ 368
            ::::|::|...:.: .||.||.|||:.||||.||...:.....|  |....:.|....|..|...
Zfish   361 TTFLKMADSGGMPQITQPGKLTEAFKYFLQGMGYIAYMKDRRMS--GGPVPSASMTRLARSRTAS 423

  Fly   369 QQAMEERDRERERERDRQRQLSLRVGNRLRETAINCTSSNSNTTAGQ 415
            ..:....|..|.|.                     ||.|:|:...||
Zfish   424 LTSAGSVDGSRNRA---------------------CTHSDSSEGVGQ 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MESK2	NP_995914.1	Abhydrolase	51..337	CDD:304388	118/288 (41%)
		MhpC	57..334	CDD:223669	114/279 (41%)
ndrg4	XP_005163134.1	Ndr	114..396	CDD:251726	120/293 (41%)
		MhpC	168..391	CDD:223669	95/234 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595955
Domainoid	1	1.000	228	1.000	Domainoid score	I2419
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	236	1.000	Inparanoid score	I3357
OMA	1	1.010	-	-		QHG55737
OrthoDB	1	1.010	-	-		D359278at33208
OrthoFinder	1	1.000	-	-		FOG0000626
OrthoInspector	1	1.000	-	-		otm24967
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11034
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X370
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	11.010