Protein Alignment MESK2 and Ndrg4

DIOPT Version :9

• Sequence 1: NP_995914.1
• Gene: MESK2 / 37451
• FlyBaseID: FBgn0043070
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_001258020.1
• Gene: Ndrg4 / 64457
• RGDID: 621593
• Length: 404
• Species: Rattus norvegicus
• Alignment Length: 390
• Identity: 136/390 - (34%)
• Similarity: 193/390 - (49%)
• Gaps: 39/390 - (10%)

  Fly    30 SVQLQFPNARGSILEA-CEQRRVPTDKGDVHVAIQGDTA--KPAIITYHDLGLNYATSFAGFFNF 91
            :.:|..|:|..|:::. .::..:.|..|.:||.|:|...  :|||:||||:|||:...|...||.
  Rat    41 ATELDNPDAFLSVVDTDWKEHDIETPYGLLHVVIRGSPKGNRPAILTYHDVGLNHKLCFNTLFNL 105

  Fly    92 PVMRGLLENFCVYHVTAPGQEEGAPTLPEDYVYPTMDDLAAQLLFVLSHFGLKSVIGFGVGAGAN 156
            ..|:.:.::|.|.||.||||:.||...|:.|.:|:|:.||..|..|:.|||.|.|||.||||||.
  Rat   106 EDMQEITKHFVVCHVDAPGQQVGASQFPQGYQFPSMEQLATMLPSVVQHFGFKYVIGIGVGAGAY 170

  Fly   157 ILARFAHAHPDKVGALCLINCVSTQSGWIEWGYQSFNARFLRTKGMTQGVIDYLMWHHFGRNPEE 221
            :||:||...||.|..|.|:|......|||:|.       ..:..|:|..:.|.::.|.|.:....
  Rat   171 VLAKFALIFPDLVEGLVLMNIDPNGKGWIDWA-------ATKLSGLTSTLPDTVLSHLFSQEELV 228

  Fly   222 RNHDLVQMYKQHFERGVNPTNLAMLINAYIHRNDLHLARTPPGTPGSETAATTLKMPVINITGSL 286
            .|.:|||.|:|.....||..||.:..|.|..|.||.:.|     ||:...|.||:.||:.:.|..
  Rat   229 NNTELVQSYRQQISSVVNQANLQLFWNMYNSRRDLDINR-----PGTVPNAKTLRCPVMLVVGDN 288

  Fly   287 SPHVDDTVTFNGRLDPTNSSWMKISDC-ALVLEEQPAKLAEAFRLFLQGEGYATPLSTPASSPCG 350
            :|..|..|..|.:||||.::::|::|. .|....||.||.|||:.||||.||...|.....|  |
  Rat   289 APAEDGVVECNSKLDPTTTTFLKMADSGGLPQVTQPGKLTEAFKYFLQGMGYIAHLKDRRLS--G 351

  Fly   351 TKYHTYSSIFFANFREQQQQAMEERDRERERERDRQRQLSLRVGNRLRETAINCTSSNSNTTAGQ 415
            ....:.|....|..|.....:....|..|.:.                     ||.|:|:...||
  Rat   352 GAVPSASMTRLARSRTASLTSASSVDGSRPQP---------------------CTHSDSSEGMGQ 395

  Fly   416  415
              Rat   396  395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MESK2	NP_995914.1	Abhydrolase	51..337	CDD:304388	116/288 (40%)
		MhpC	57..334	CDD:223669	112/279 (40%)
Ndrg4	NP_001258020.1	Ndr	60..342	CDD:397285	118/293 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353799
Domainoid	1	1.000	235	1.000	Domainoid score	I2277
eggNOG	1	0.900	-	-		E1_KOG2931
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	242	1.000	Inparanoid score	I3236
OMA	1	1.010	-	-		QHG55737
OrthoDB	1	1.010	-	-		D359278at33208
OrthoFinder	1	1.000	-	-		FOG0000626
OrthoInspector	1	1.000	-	-		otm44451
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11034
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X370
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910