Protein Alignment MESK2 and Ndrg1

DIOPT Version :9

• Sequence 1: NP_995914.1
• Gene: MESK2 / 37451
• FlyBaseID: FBgn0043070
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_032707.2
• Gene: Ndrg1 / 17988
• MGIID: 1341799
• Length: 394
• Species: Mus musculus
• Alignment Length: 396
• Identity: 142/396 - (35%)
• Similarity: 205/396 - (51%)
• Gaps: 52/396 - (13%)

  Fly    47 EQRRVPTDKGDVHVAIQGDTA--KPAIITYHDLGLNYATSFAGFFNFPVMRGLLENFCVYHVTAP 109
            :::.:.|..|.:||.:.|...  :|.|:||||:|:|:.|.:...||...|:.:.::|.|.||.||
Mouse    33 QEQDIETLHGSLHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNSEDMQEITQHFAVCHVDAP 97

  Fly   110 GQEEGAPTLPEDYVYPTMDDLAAQLLFVLSHFGLKSVIGFGVGAGANILARFAHAHPDKVGALCL 174
            ||::|||:.|..|:||:||.||..|..||..||||||||.|.||||.||.|||..:|:.|..|.|
Mouse    98 GQQDGAPSFPVGYMYPSMDQLAEMLPGVLHQFGLKSVIGMGTGAGAYILTRFALNNPEMVEGLVL 162

  Fly   175 INCVSTQSGWIEWGYQSFNARFLRTKGMTQGVIDYLMWHHFGRNPEERNHDLVQMYKQHFERGVN 239
            :|......||::|...       :..|.||.:.|.::.|.||:.....|.::|..|:||....:|
Mouse   163 MNVNPCAEGWMDWAAS-------KISGWTQALPDMVVSHLFGKEEIHNNVEVVHTYRQHILNDMN 220

  Fly   240 PTNLAMLINAYIHRNDLHLARTPPGTPGSETAATTLKMPVINITGSLSPHVDDTVTFNGRLDPTN 304
            |:||.:.|:||..|.||.:.|..||     |...||:.|.:.:.|..||.||..|..|.:||||.
Mouse   221 PSNLHLFISAYNSRRDLEIERPMPG-----THTVTLQCPALLVVGDNSPAVDAVVECNSKLDPTK 280

  Fly   305 SSWMKISDC-ALVLEEQPAKLAEAFRLFLQGEGY------------ATPLSTPASSPCGTKYHTY 356
            ::.:|::|| .|....|||||||||:.|:||.||            .|...:..:|..||:..::
Mouse   281 TTLLKMADCGGLPQISQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLEGTRSRSH 345

  Fly   357 SSIFFANFREQQQQAMEERDRERERERDRQRQLSLRVGNRLRETAINCTSSNSNTTAGQGDNNNA 421
            :|               |..|.|....:..|..|    :...:..:|.| .||..|     .|||
Mouse   346 TS---------------EGPRSRSHTSEGSRSRS----HTSEDARLNIT-PNSGAT-----GNNA 385

  Fly   422 DGRSVD 427
            ..:|::
Mouse   386 GPKSME 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MESK2	NP_995914.1	Abhydrolase	51..337	CDD:304388	121/288 (42%)
		MhpC	57..334	CDD:223669	117/279 (42%)
Ndrg1	NP_032707.2	Ndr	34..316	CDD:335213	123/293 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	325..394		19/92 (21%)
		3 X 10 AA tandem repeats of G-[PST]-R-S-R-S-H-T-S-E	339..368		8/47 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850102
Domainoid	1	1.000	234	1.000	Domainoid score	I2376
eggNOG	1	0.900	-	-		E1_KOG2931
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	241	1.000	Inparanoid score	I3317
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55737
OrthoDB	1	1.010	-	-		D359278at33208
OrthoFinder	1	1.000	-	-		FOG0000626
OrthoInspector	1	1.000	-	-		otm42388
orthoMCL	1	0.900	-	-		OOG6_103361
Panther	1	1.100	-	-	O	PTHR11034
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5286
SonicParanoid	1	1.000	-	-		X370
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.840