Protein Alignment MESK2 and Ndrg2

DIOPT Version :10

• Sequence 1: NP_995914.1
• Gene: MESK2 / 37451
• FlyBaseID: FBgn0043070
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: XP_063129996.1
• Gene: Ndrg2 / 171114
• RGDID: 621874
• Length: 385
• Species: Rattus norvegicus
• Alignment Length: 376
• Identity: 127/376 - (33%)
• Similarity: 184/376 - (48%)
• Gaps: 50/376 - (13%)

  Fly    27 ELRSVQL--QFPNARGSILEACEQ----RRVPTDKGDVH----------VAIQG--DTAKPAIIT 73
            ||:.||:  :.|...|...||.::    .|:..|:|..|          ..:.|  ...:|||.|
  Rat    17 ELQEVQITEEKPLLPGQTPEAAKEAELAARILLDQGQTHSVETPYGSVTFTVYGTPKPKRPAIFT 81

  Fly    74 YHDLGLNYATSFAGFFNFPVMRGLLENFCVYHVTAPGQEEGAPTLPEDYVYPTMDDLAAQLLFVL 138
            |||:||||.:.|...|.|..|:.:::||...||.|||.|||||..|..|.||::|.||..:..:|
  Rat    82 YHDVGLNYKSCFQPLFQFGDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCIL 146

  Fly   139 SHFGLKSVIGFGVGAGANILARFAHAHPDKVGALCLINCVSTQSGWIEWGYQSFNARFLRTKGMT 203
            .:....::||.||||||.||:|:|..|||.|..|.|||......||::|...       :..|:|
  Rat   147 QYLNFSTIIGVGVGAGAYILSRYALNHPDTVEGLVLINIDPNAKGWMDWAAH-------KLTGLT 204

  Fly   204 QGVIDYLMWHHFGRNPEERNHDLVQMYKQHFERGVNPTNLAMLINAYIHRNDLHLARTPPGTPGS 268
            ..:.:.::.|.|.:.....|.:|:|.|:.......|..|:.:..|:|.:|.||:..|      |.
  Rat   205 SSIPEMILGHLFSQEELSGNSELIQKYRSLITHAPNLENIELYWNSYNNRRDLNFER------GG 263

  Fly   269 ETAATTLKMPVINITGSLSPHVDDTVTFNGRLDPTNSSWMKISDCALVLE-EQPAKLAEAFRLFL 332
            |   .|||.||:.:.|..:||.|..|..|.:||||.:|::|::|.....: .||.||.|||:.|:
  Rat   264 E---MTLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFV 325

  Fly   333 QGEGYATPLSTPASSPCGTKYHTYSSIFFANFREQQQQAMEERDRERERER 383
            ||.||       .:|.|.|:        .:..|.....:....|..|.|.|
  Rat   326 QGMGY-------MASSCMTR--------LSRSRTASLTSAASIDGSRSRSR 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MESK2	NP_995914.1	alpha/beta hydrolases	51..337	CDD:473884	108/298 (36%)
Ndrg2	XP_063129996.1	None