DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp14 and FKBP6

DIOPT Version :9

Sequence 1:	NP_001246448.1	Gene:	Fkbp14 / 37449	FlyBaseID:	FBgn0010470	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_003593.3	Gene:	FKBP6 / 8468	HGNCID:	3722	Length:	327	Species:	Homo sapiens

Alignment Length:	86	Identity:	30/86 - (34%)
Similarity:	48/86 - (55%)	Gaps:	0/86 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 SLTMHYTGTLQADGKKFDSSFDRDQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGYGD 110
            |:.:.|:|.|:...:.|||::.|..|...:||....:.|.:.|||:|..||..:....|...||.
Human    56 SVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGT 120

  Fly   111 QGAGNVIPPKATLLFDVELIN 131
            .|...:|||..|:||::||::
Human   121 LGCPPLIPPNTTVLFEIELLD 141

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	29/83 (35%)
		EF-hand_7	140..212	CDD:290234
		EFh	141..212	CDD:298682
FKBP6	NP_003593.3	FKBP_C	51..140	CDD:306713	29/83 (35%)
		TPR	<164..315	CDD:223533
		TPR 1	171..204
		TPR 2	219..252
		TPR repeat	221..247	CDD:276809
		TPR repeat	252..282	CDD:276809
		TPR 3	253..286
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810