DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp14 and PAS1

DIOPT Version :9

Sequence 1:	NP_001246448.1	Gene:	Fkbp14 / 37449	FlyBaseID:	FBgn0010470	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_566993.1	Gene:	PAS1 / 824568	AraportID:	AT3G54010	Length:	635	Species:	Arabidopsis thaliana

Alignment Length:	161	Identity:	46/161 - (28%)
Similarity:	70/161 - (43%)	Gaps:	19/161 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LTMHYTGTLQADGKK--FDSSFD-RDQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGY 108
            |::||.|.|..:.|.  :||..| .|||..|..|.|.|.:|::.....|..||...:|.||...|
plant   294 LSVHYKGMLLNEEKTVFYDSKIDNNDQPLEFSSGEGLVPEGFEMCTRLMLPGEIALVTCPPDYAY 358

  Fly   109 GDQGAGNVIPPKATLLFDVELINIGNAPPTTNV-FKEIDDNADK------QLSRE---EVIVYVS 163
            ........:...|.:.:::||:........|.: |:.|.|.|||      :|.:|   |:.....
plant   359 DKFPRPPGVSEGAHVQWEIELLGFETPRDWTGLNFQSIMDEADKIRSTGNRLFKEGKFELAKAKY 423

  Fly   164 EYLKKQMTAVEGQDSEE------LKNMLAEN 188
            |.:.::...|..||.:|      .:|||..|
plant   424 EKVLREFNHVNPQDEDEGKIFGDTRNMLHLN 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	26/85 (31%)
		EF-hand_7	140..212	CDD:290234	18/65 (28%)
		EFh	141..212	CDD:298682	18/64 (28%)
PAS1	NP_566993.1	FKBP_C	44..144	CDD:278674
		FKBP_C	168..257	CDD:302890
		FKBP_C	291..380	CDD:278674	26/85 (31%)
		TPR_11	399..480	CDD:290150	15/56 (27%)
		TPR repeat	437..478	CDD:276809	6/18 (33%)
		TPR_11	451..514	CDD:290150	2/4 (50%)
		TPR repeat	483..511	CDD:276809
		TPR repeat	516..543	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810