DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp14 and TWD1

DIOPT Version :9

Sequence 1:	NP_001246448.1	Gene:	Fkbp14 / 37449	FlyBaseID:	FBgn0010470	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_188801.2	Gene:	TWD1 / 821718	AraportID:	AT3G21640	Length:	365	Species:	Arabidopsis thaliana

Alignment Length:	191	Identity:	45/191 - (23%)
Similarity:	82/191 - (42%)	Gaps:	44/191 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 DLKVEVISTPEVCEQKSKNG--------DSLTMHYTGTLQADGKKFDSSFDRDQPFTFQLG---- 77
            |.:.||:. .:|.:|..|.|        .:..:||....:....||:.::...||....||
plant    41 DSEAEVLD-EKVSKQIIKEGHGSKPSKYSTCFLHYRAWTKNSQHKFEDTWHEQQPIELVLGKEKK 104

  Fly    78 --AGQVIKGWDQGLLNMCVGEKRKLTIPPQLGYGDQGAGNV--IPPKATLLFDVELINIGNAPPT 138
              ||..|     |:.:|..||:..:.:..:|.||.:|..:.  :||.|.||::||:|..
plant   105 ELAGLAI-----GVASMKSGERALVHVGWELAYGKEGNFSFPNVPPMADLLYEVEVIGF------ 158

  Fly   139 TNVFKEIDDNADKQLSREEVIVYVSEYLKKQMTAVEGQDSEELKNMLAENDKLVEEIFQHE 199
                    |...:..:|.::.|      ::::.|.:.:..:  .|.|.:.:||.|.:.|:|
plant   159 --------DETKEGKARSDMTV------EERIGAADRRKMD--GNSLFKEEKLEEAMQQYE 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	29/108 (27%)
		EF-hand_7	140..212	CDD:290234	11/60 (18%)
		EFh	141..212	CDD:298682	11/59 (19%)
TWD1	NP_188801.2	FKBP_C	62..156	CDD:395196	26/98 (27%)
		PRK15331	196..310	CDD:357168	3/8 (38%)
		TPR repeat	230..259	CDD:276809
		TPR repeat	264..292	CDD:276809
		TPR repeat	298..323	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900