Protein Alignment Fkbp14 and FKBP7

DIOPT Version :10

• Sequence 1: NP_001246448.1
• Gene: Fkbp14 / 37449
• FlyBaseID: FBgn0010470
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_851939.1
• Gene: FKBP7 / 51661
• HGNCID: 3723
• Length: 222
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 82/200 - (41%)
• Similarity: 118/200 - (59%)
• Gaps: 13/200 - (6%)

  Fly    24 QDLKVEVISTPEVCEQKSKNGDSLTMHYTGTLQADGKKFDSSFDRDQ--PFTFQLGAGQVIKGWD 86
            :::|:||:..||.|.:.||.||.|..||.|.|..||.||..|..:::  |..|.||.||||||.|
Human    33 EEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGLD 97

  Fly    87 QGLLNMCVGEKRKLTIPPQLGYGDQG-AGNVIPPKATLLFDVELINIGNAPPTTNVFKEIDDNAD 150
            ..:.:||.|||||:.|||...||.:| |...|||.|||:|::||..:...|.:...||:||.:.|
Human    98 IAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTKGPRSIETFKQIDMDND 162

  Fly   151 KQLSREEVIVYVSEYLKKQMTAVEGQDSEELKNMLAENDKLVEEIFQHEDKDKNGFISHDEFSGP 215
            :|||:.|:.:|:....:|          :|.....:..|.::|:||:..|.|.:||||..|::..
Human   163 RQLSKAEINLYLQREFEK----------DEKPRDKSYQDAVLEDIFKKNDHDGDGFISPKEYNVY 217

  Fly   216 KHDEL 220
            :||||
Human   218 QHDEL 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:459735	48/95 (51%)
		FRQ1	<142..212	CDD:444056	22/69 (32%)
FKBP7	NP_851939.1	FKBP_C	46..141	CDD:459735	47/94 (50%)
		FRQ1	<127..213	CDD:444056	32/95 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..222		9/21 (43%)
		Retention in the endoplasmic reticulum. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	219..222		2/2 (100%)