DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp14 and fkbp16

DIOPT Version :9

Sequence 1:	NP_001246448.1	Gene:	Fkbp14 / 37449	FlyBaseID:	FBgn0010470	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_001373781.1	Gene:	fkbp16 / 497400	ZFINID:	ZDB-GENE-050208-116	Length:	504	Species:	Danio rerio

Alignment Length:	161	Identity:	35/161 - (21%)
Similarity:	62/161 - (38%)	Gaps:	19/161 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GDSLTMHYTGTLQADGKKFDSS-FDRDQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLG 107
            |..:|:...|.|:      |.: .::|....|.:|.|.|.:..::..:.|..||...|....|..
Zfish   207 GQEVTLKMQGVLE------DRTVVEKDSKLVFIIGEGDVTQALEECAITMKKGEIALLLADSQYT 265

  Fly   108 YGDQGAGNVIPPKATLLFDVELINIGN--------APPTTNVFKEIDDNADKQLSREEVIVYVSE 164
            ||..|....||..|.||:.::|::...        .|....:..:..:..:....|||....|..
Zfish   266 YGLLGREPDIPAWAPLLYQLQLLDFREKPDPLLLPVPDRIRIGNQKRERGNFYFQREEFSKAVQA 330

  Fly   165 Y-LKKQMTAVEGQDSEELKNMLAENDKLVEE 194
            | :...:......|.:   |.:||.::.|.:
Zfish   331 YCMALDVLTTRTNDGQ---NCVAEEEEEVND 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	23/86 (27%)
		EF-hand_7	140..212	CDD:290234	10/56 (18%)
		EFh	141..212	CDD:298682	10/55 (18%)
fkbp16	NP_001373781.1	FKBP_C	203..288	CDD:418595	23/86 (27%)
		TPR	<305..427	CDD:223533	10/57 (18%)
		TPR repeat	312..355	CDD:276809	9/45 (20%)
		TPR repeat	360..390	CDD:276809
		TPR_19	372..438	CDD:405276
		TPR repeat	395..423	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900