DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp14 and fkbp14

DIOPT Version :9

Sequence 1:	NP_001246448.1	Gene:	Fkbp14 / 37449	FlyBaseID:	FBgn0010470	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_001005108.1	Gene:	fkbp14 / 448687	XenbaseID:	XB-GENE-949902	Length:	206	Species:	Xenopus tropicalis

Alignment Length:	217	Identity:	94/217 - (43%)
Similarity:	134/217 - (61%)	Gaps:	14/217 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LVISCLLLVAISNSLVRAQDLKVEVISTPEVCEQKSKNGDSLTMHYTGTLQADGKKFDSSF--DR 68
            |||..:||...|.:|:...:::::|:..|.:|.:||||||.|.:|..|.|:.:|.:|.|::  :.
Frog     2 LVIVAVLLACASGALIPEPEVQIQVLEKPFICRRKSKNGDLLLVHAEGFLEKNGSRFHSTYKENN 66

  Fly    69 DQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGYGDQGAGNVIPPKATLLFDVELINIG 133
            .||..|.||..:||||||:||.:||||||.||.:||.|.||.:|.|. |||::||:|:::|:.|.
Frog    67 GQPVWFTLGIREVIKGWDKGLQDMCVGEKSKLIVPPALAYGKEGKGK-IPPESTLIFNIDLMEIR 130

  Fly   134 NAPPTTNVFKEIDDNADKQLSREEVIVYVSEYLKKQMTAVEGQDSEELKNMLAENDKLVEEIFQH 198
            |.|.:...|:|:|.|.|.:||:|||..|:.....|....|...|.|          .|||.||:.
Frog   131 NGPRSHESFQEMDLNDDWKLSKEEVKAYLKNEFGKHGGNVNDTDHE----------VLVESIFEK 185

  Fly   199 EDKDKNGFISHDEFSGPKHDEL 220
            ||:|.:||||..||: ..||||
Frog   186 EDEDNDGFISAREFT-YVHDEL 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	48/94 (51%)
		EF-hand_7	140..212	CDD:290234	27/71 (38%)
		EFh	141..212	CDD:298682	27/70 (39%)
fkbp14	NP_001005108.1	FKBP_C	33..126	CDD:306713	48/93 (52%)
fkbp14	NP_001005108.1	EF-hand_7	136..199	CDD:316058	27/72 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I12024
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H23059
Inparanoid	1	1.050	163	1.000	Inparanoid score	I4095
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1507309at2759
OrthoFinder	1	1.000	-	-		FOG0008313
OrthoInspector	1	1.000	-	-		otm48297
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2163
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060