DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp14 and fkbp9

DIOPT Version :9

Sequence 1:	NP_001246448.1	Gene:	Fkbp14 / 37449	FlyBaseID:	FBgn0010470	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_001003520.1	Gene:	fkbp9 / 445126	ZFINID:	ZDB-GENE-040801-23	Length:	564	Species:	Danio rerio

Alignment Length:	213	Identity:	75/213 - (35%)
Similarity:	115/213 - (53%)	Gaps:	33/213 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 VEVISTP-EVCEQKSKNGDSLTMHYTGTLQADGKKFDSSFDRDQPFTFQLGAGQVIKGWDQGLLN 91
            ||:.|.. |.|...:|.||.:..||..||. ||....|:....:.:...||:|||:.|.:|||..
Zfish   365 VEITSVKLENCTYNAKRGDFVKYHYNATLM-DGTDIGSTHMYGKTYNVVLGSGQVVIGMEQGLTG 428

  Fly    92 MCVGEKRKLTIPPQLGYGDQGAGNVIPPKATLLFDVELINIGNAPP-----------TTNVFKEI 145
            ||:||||||.|||.|.||::|....:|..|.|:|:||::::....|           |.::|.|:
Zfish   429 MCIGEKRKLVIPPHLAYGERGVDGEVPGSAVLVFEVEMVDVEEGLPEGYMFVWNNNVTPDLFSEM 493

  Fly   146 DDNADKQLSREEVIVYVSEYLKKQMTAVEGQDSEELKNMLA---ENDKLVEEIFQHEDKDKNGFI 207
            |.|.|.|:.:.|    .|:|:.:|:        ||.|..||   |:.:::|.::.::|::|:|.|
Zfish   494 DKNKDAQVDKTE----FSDYILQQV--------EEGKGRLAPGFESQRIIESMYDNQDRNKDGII 546

  Fly   208 SHDEF-----SGPKHDEL 220
            :.|||     ....||||
Zfish   547 TEDEFKLKADEAAAHDEL 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	41/92 (45%)
		EF-hand_7	140..212	CDD:290234	22/74 (30%)
		EFh	141..212	CDD:298682	22/73 (30%)
fkbp9	NP_001003520.1	FKBP_C	40..132	CDD:278674
		FKBP_C	152..244	CDD:278674
		FKBP_C	264..356	CDD:278674
		FKBP_C	375..467	CDD:278674	41/92 (45%)
		EF-hand_7	488..552	CDD:290234	23/75 (31%)
		EFh	490..551	CDD:298682	22/72 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1507309at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820