DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp14 and fkbp14

DIOPT Version :9

Sequence 1:	NP_001246448.1	Gene:	Fkbp14 / 37449	FlyBaseID:	FBgn0010470	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_001003471.1	Gene:	fkbp14 / 445077	ZFINID:	ZDB-GENE-040801-210	Length:	211	Species:	Danio rerio

Alignment Length:	204	Identity:	99/204 - (48%)
Similarity:	131/204 - (64%)	Gaps:	26/204 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 DLKVEVISTPEVCEQKSKNGDSLTMHYTGTLQADGKKFDSSFDRDQ----PFTFQLGAGQVIKGW 85
            ::|:||:..|.:|.:|||.||.|.:||.|.|:::|..|.||  |.|    |..|.||..:|||||
Zfish    26 EVKIEVLYKPFLCHRKSKYGDILLVHYDGFLESNGTMFHSS--RHQGDKNPVWFTLGIREVIKGW 88

  Fly    86 DQGLLNMCVGEKRKLTIPPQLGYGDQGAGNVIPPKATLLFDVELINIGNAPPTTNVFKEIDDNAD 150
            |:||.|||.||||||||||.|.||.:|.|. |||::||:||:|:|.|.|.|.:...|:|:|.|.|
Zfish    89 DKGLQNMCAGEKRKLTIPPALAYGKEGKGK-IPPESTLIFDIEIIEIRNGPRSHESFQEMDLNDD 152

  Fly   151 KQLSREEVIVYVSEYLKKQMTAVEGQDSEELKNMLAENDK----LVEEIFQHEDKDKNGFISHDE 211
            .:||:.|    |.|||:|:..          |:..|.||.    :||:|||.||:||:||||..|
Zfish   153 WKLSKAE----VKEYLRKEFE----------KHGYAANDTHHEVMVEDIFQKEDEDKDGFISSRE 203

  Fly   212 FSGPKHDEL 220
            |: .:||||
Zfish   204 FT-YQHDEL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	55/96 (57%)
		EF-hand_7	140..212	CDD:290234	30/75 (40%)
		EFh	141..212	CDD:298682	30/74 (41%)
fkbp14	NP_001003471.1	FKBP_C	38..132	CDD:278674	55/96 (57%)
		EF-hand_7	141..204	CDD:290234	30/76 (39%)
		EFh	142..204	CDD:298682	30/75 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I12028
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23059
Inparanoid	1	1.050	168	1.000	Inparanoid score	I4129
OMA	1	1.010	-	-		QHG50085
OrthoDB	1	1.010	-	-		D1507309at2759
OrthoFinder	1	1.000	-	-		FOG0008313
OrthoInspector	1	1.000	-	-		otm24953
orthoMCL	1	0.900	-	-		OOG6_101705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2163
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.780