DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp14 and fkbp5

DIOPT Version :9

Sequence 1:	NP_001246448.1	Gene:	Fkbp14 / 37449	FlyBaseID:	FBgn0010470	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	XP_005166078.1	Gene:	fkbp5 / 368924	ZFINID:	ZDB-GENE-030616-630	Length:	477	Species:	Danio rerio

Alignment Length:	88	Identity:	42/88 - (47%)
Similarity:	57/88 - (64%)	Gaps:	1/88 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GDSLTMHYTGTLQADGKKFDSSFDRDQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGY 108
            ||.:.:||||.| ..|||||||.||.:||.|.:|.|||||.||..:.:|..||...:...|:..|
Zfish    74 GDRVFVHYTGRL-LSGKKFDSSLDRKEPFVFNVGKGQVIKAWDICVCSMQKGEVCLMLCKPEYAY 137

  Fly   109 GDQGAGNVIPPKATLLFDVELIN 131
            |..|:...:||.:||:|::||:|
Zfish   138 GSAGSPPKVPPNSTLVFEIELLN 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	40/85 (47%)
		EF-hand_7	140..212	CDD:290234
		EFh	141..212	CDD:298682
fkbp5	XP_005166078.1	FKBP_C	69..159	CDD:278674	40/85 (47%)
		FkpA	<167..271	CDD:223619
		TPR_11	291..372	CDD:290150
		TPR repeat	292..320	CDD:276809
		TPR repeat	340..370	CDD:276809
		TPR_11	343..405	CDD:290150
		TPR	343..374	CDD:197478
		TPR repeat	375..403	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810