DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp14 and Fkbp14

DIOPT Version :9

Sequence 1:	NP_001246448.1	Gene:	Fkbp14 / 37449	FlyBaseID:	FBgn0010470	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_001013228.1	Gene:	Fkbp14 / 362366	RGDID:	1311705	Length:	211	Species:	Rattus norvegicus

Alignment Length:	212	Identity:	95/212 - (44%)
Similarity:	134/212 - (63%)	Gaps:	14/212 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLLVAISNSLVRAQDLKVEVISTPEVCEQKSKNGDSLTMHYTGTLQADGKKFDSS--FDRDQPFT 73
            |.:..:|.:|:...::|:||:..|.:|.:|:|.||.:.:||.|.|:.||..|.|:  .:..||..
  Rat    12 LWVTVLSGALIPEPEVKIEVLQKPFICHRKTKGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPVW 76

  Fly    74 FQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGYGDQGAGNVIPPKATLLFDVELINIGNAPPT 138
            |.||..:|:|||||||..|||||||||||||.||||.:|.|. |||::||:|:::|:.|.|.|.:
  Rat    77 FTLGILEVLKGWDQGLKGMCVGEKRKLTIPPALGYGKEGKGK-IPPESTLIFNIDLLEIRNGPRS 140

  Fly   139 TNVFKEIDDNADKQLSREEVIVYVSEYLKKQMTAVEGQDSEELKNMLAENDKLVEEIFQHEDKDK 203
            ...|:|:|.|.|.:||:.||.||:....:|....|..          :.:|.|||:||..||:||
  Rat   141 HESFQEMDLNDDWKLSKHEVKVYLQNEFEKHGAVVNE----------SHHDALVEDIFDKEDEDK 195

  Fly   204 NGFISHDEFSGPKHDEL 220
            :||||..||: ..||||
  Rat   196 DGFISAREFT-YVHDEL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	51/94 (54%)
		EF-hand_7	140..212	CDD:290234	27/71 (38%)
		EFh	141..212	CDD:298682	27/70 (39%)
Fkbp14	NP_001013228.1	FKBP_C	38..132	CDD:395196	52/95 (55%)
Fkbp14	NP_001013228.1	EF-hand_7	141..204	CDD:404394	21/62 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11370
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23059
Inparanoid	1	1.050	176	1.000	Inparanoid score	I3940
OMA	1	1.010	-	-		QHG50085
OrthoDB	1	1.010	-	-		D1507309at2759
OrthoFinder	1	1.000	-	-		FOG0008313
OrthoInspector	1	1.000	-	-		otm45231
orthoMCL	1	0.900	-	-		OOG6_101705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2163
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.780