DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp14 and Fkbp15

DIOPT Version :9

Sequence 1:	NP_001246448.1	Gene:	Fkbp14 / 37449	FlyBaseID:	FBgn0010470	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	XP_006538097.1	Gene:	Fkbp15 / 338355	MGIID:	2444782	Length:	1255	Species:	Mus musculus

Alignment Length:	209	Identity:	56/209 - (26%)
Similarity:	91/209 - (43%)	Gaps:	42/209 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKSNLVISCLLLVAISNSLVRAQDLKVEVISTPEVCEQKSKNGDSLTMHYTGTLQAD---GKKF 62
            ::|.|.:.|  |...:...||.|:...||             .||||.:.|||.|..:   |:.|
Mouse   168 VAKCNSISS--LDAVLCQDLVAAEGPAVE-------------TGDSLEVAYTGWLLQNHVLGQVF 217

  Fly    63 DSSFDRDQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGYGDQGA-GNVIPPKATLLFD 126
            ||:.::|:|...:||:|:|:||.:.|||.|..|.||.:..|.....|.:|. |...|..:.|:|:
Mouse   218 DSTANKDKPLRLKLGSGKVVKGLEDGLLGMKKGGKRLIITPSACAAGSEGVIGWTQPTDSILVFE 282

  Fly   127 VELINI---------GNAPPTTNVFKEIDDNADKQLSREEVIVYV--------------SEYLKK 168
            ||:..:         |::..:.:........|...||.:.|:..:              |..|.:
Mouse   283 VEVRRVKFARDSGSDGHSVSSRDSAAPSPIPASDSLSADPVVTPLPLPLKPGEPGLRSKSNSLSE 347

  Fly   169 QMTAVEGQDSEELK 182
            |:|.....|:.:.|
Mouse   348 QLTVNSNPDTVKAK 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	36/96 (38%)
		EF-hand_7	140..212	CDD:290234	10/57 (18%)
		EFh	141..212	CDD:298682	10/56 (18%)
Fkbp15	XP_006538097.1	FKBP_C	192..285	CDD:365980	37/105 (35%)
		PRK10263	<378..>489	CDD:236669
		Smc	<561..890	CDD:224117
		PHA03247	<944..1129	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900