DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fkbp14 and Fkbp9

DIOPT Version :9

Sequence 1:NP_001246448.1 Gene:Fkbp14 / 37449 FlyBaseID:FBgn0010470 Length:220 Species:Drosophila melanogaster
Sequence 2:NP_001007647.1 Gene:Fkbp9 / 297123 RGDID:1549757 Length:570 Species:Rattus norvegicus


Alignment Length:355 Identity:84/355 - (23%)
Similarity:136/355 - (38%) Gaps:162/355 - (45%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 KSNLVISCLLL--------VAISNSLVRAQDLKVEVISTPEVCEQKSKNGDSLTMHYTGTLQADG 59
            :::||....||        :::.|.:|            ||.||::|::||.|..||.||| .||
  Rat   241 QASLVFDVALLDLHNPKDTISVENKVV------------PESCERRSQSGDFLRYHYNGTL-LDG 292

  Fly    60 KKFDSSFDRDQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGYGDQGAGN--------- 115
            ..||||:.|:..|...:|.|.||.|.|:|||.:|:||:|::.:||.||||::|.|:         
  Rat   293 TLFDSSYSRNHTFDTYIGQGYVIPGMDEGLLGVCIGERRRIVVPPHLGYGEEGRGSIPGSAVLVF 357

  Fly   116 ----------------------------------------------------------------- 115
                                                                             
  Rat   358 DIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGF 422

  Fly   116 ----------------------VIPP---------------KATLLFDVELIN-----------I 132
                                  :|||               .|.|:||:||:.           |
  Rat   423 GQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVSGLPEGYMFI 487

  Fly   133 GNAPPTTNVFKEIDDNADKQLSREEVIVYVSEYLKKQMTAVEGQDSEELKNMLAEN---DKLVEE 194
            .|...:.|:|:|||.:.:.::..||    .|||:..|:.:.:|:        ||..   :.:|:.
  Rat   488 WNGEVSPNLFEEIDKDGNGEVLLEE----FSEYIHAQVASGKGK--------LAPGFNAEMIVKN 540

  Fly   195 IFQHEDKDKNGFISHDEF----SGPKHDEL 220
            :|.::|::.:|.::.:||    ...|||||
  Rat   541 MFTNQDRNGDGKVTAEEFKLKDQETKHDEL 570

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fkbp14NP_001246448.1 FKBP_C 37..130 CDD:278674 48/203 (24%)
EF-hand_7 140..212 CDD:290234 18/74 (24%)
EFh 141..212 CDD:298682 17/73 (23%)
Fkbp9NP_001007647.1 FKBP_C 47..139 CDD:278674
FKBP_C 159..251 CDD:278674 2/9 (22%)
FKBP_C 271..362 CDD:278674 40/91 (44%)
FKBP_C 382..474 CDD:278674 8/91 (9%)
EF-hand_7 495..559 CDD:290234 19/75 (25%)
EFh 497..558 CDD:238008 17/72 (24%)
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 567..570 2/2 (100%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0545
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1507309at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.820

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