DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp14 and fkb-6

DIOPT Version :9

Sequence 1:	NP_001246448.1	Gene:	Fkbp14 / 37449	FlyBaseID:	FBgn0010470	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_508026.1	Gene:	fkb-6 / 180371	WormBaseID:	WBGene00001431	Length:	431	Species:	Caenorhabditis elegans

Alignment Length:	185	Identity:	61/185 - (32%)
Similarity:	87/185 - (47%)	Gaps:	33/185 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 KSKNGDSLTMHYTGTLQADGKKFDSSFDRDQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPP 104
            |...|.::.:||.|||: :|.|||||.||...|:|.||.|.||||||.|:..|..||..:.||..
Worm    29 KPTTGTTVKVHYVGTLE-NGTKFDSSRDRGDQFSFNLGRGNVIKGWDLGVATMTKGEVAEFTIRS 92

  Fly   105 QLGYGDQGAGNVIPPKATLLFDVELINIGNAPPTTNVFKEIDDNADKQLSR-------------- 155
            ..||||.|:...||..|||:|:|||....        .::|..:.|..:.|
Worm    93 DYGYGDAGSPPKIPGGATLIFEVELFEWS--------AEDISPDRDGTILRTIIVEGSKNSFPND 149

  Fly   156 -EEVIVYV------SEYLKKQMTAVEGQDSEELKNMLAENDKLVEEIFQHEDKDK 203
             .:|:.:.      :|:..:::....|:.|||   .|.|..:.....||..:|.|
Worm   150 TSKVLAHCVGTYQGTEFYNREVNFHIGEGSEE---GLPEGVERALRRFQLGEKSK 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	45/89 (51%)
		EF-hand_7	140..212	CDD:290234	15/85 (18%)
		EFh	141..212	CDD:298682	15/84 (18%)
fkb-6	NP_508026.1	FKBP_C	26..117	CDD:278674	44/88 (50%)
		TPR_11	254..334	CDD:290150
		TPR repeat	254..282	CDD:276809
		TPR repeat	291..332	CDD:276809
		TPR_11	305..368	CDD:290150
		TPR_1	337..370	CDD:278916
		TPR repeat	337..365	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810