Protein Alignment Fkbp14 and Fkbp7

DIOPT Version :9

• Sequence 1: NP_001246448.1
• Gene: Fkbp14 / 37449
• FlyBaseID: FBgn0010470
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_034352.1
• Gene: Fkbp7 / 14231
• MGIID: 1336879
• Length: 218
• Species: Mus musculus
• Alignment Length: 200
• Identity: 81/200 - (40%)
• Similarity: 118/200 - (59%)
• Gaps: 13/200 - (6%)

  Fly    24 QDLKVEVISTPEVCEQKSKNGDSLTMHYTGTLQADGKKFDSSFDRDQ--PFTFQLGAGQVIKGWD 86
            :::|:||:..||.|.:.|:.||.|..||.|.|..||.||..|..:|:  |..|.||.|.||||.|
Mouse    29 EEVKIEVLHRPENCSKTSRKGDLLNAHYDGYLAKDGSKFYCSRTQDEGHPKWFVLGVGHVIKGLD 93

  Fly    87 QGLLNMCVGEKRKLTIPPQLGYGDQG-AGNVIPPKATLLFDVELINIGNAPPTTNVFKEIDDNAD 150
            ..:::||.|||||:.|||...||.:| |...|||.|||:|::||..:...|.:...||:||.:.|
Mouse    94 IAMMDMCPGEKRKVIIPPSFAYGKEGYAEGKIPPNATLMFEIELYAVTKGPRSIETFKQIDTDND 158

  Fly   151 KQLSREEVIVYVSEYLKKQMTAVEGQDSEELKNMLAENDKLVEEIFQHEDKDKNGFISHDEFSGP 215
            :|||:.|:.:|:.:..:|.   ...:|....|.:|       |:||:..|.:.:||||..|::..
Mouse   159 RQLSKAEIELYLQKDFEKD---ANPRDKSYQKAVL-------EDIFKKNDHNGDGFISPKEYNVH 213

  Fly   216 KHDEL 220
            :||||
Mouse   214 QHDEL 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	47/95 (49%)
		EF-hand_7	140..212	CDD:290234	22/71 (31%)
		EFh	141..212	CDD:298682	22/70 (31%)
Fkbp7	NP_034352.1	FKBP_C	42..137	CDD:278674	46/94 (49%)
		EF-hand_7	148..210	CDD:290234	22/71 (31%)
		EFh	148..209	CDD:298682	22/70 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..218		8/20 (40%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	215..218		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11605
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	177	1.000	Inparanoid score	I4022
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG50085
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm43162
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2163
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.870