DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fkbp14 and Fkbp4

DIOPT Version :9

Sequence 1:NP_001246448.1 Gene:Fkbp14 / 37449 FlyBaseID:FBgn0010470 Length:220 Species:Drosophila melanogaster
Sequence 2:NP_034349.1 Gene:Fkbp4 / 14228 MGIID:95543 Length:458 Species:Mus musculus


Alignment Length:204 Identity:69/204 - (33%)
Similarity:95/204 - (46%) Gaps:37/204 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 GDSLTMHYTGTLQADGKKFDSSFDRDQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGY 108
            ||.:.:||||.| .||.|||||.||...|:|.||.|:|||.||..:..|.|||...:|..|:..|
Mouse    50 GDRVFVHYTGWL-LDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAY 113

  Fly   109 GDQGAGNVIPPKATLLFDVELINIGNAPPTTNVFKEIDDNADKQL-SREE----------VIVYV 162
            |..|:...|||.|||:|:|||........|    :|.|....::: :|.|          |.|.:
Mouse   114 GAAGSPPKIPPNATLVFEVEL
FEFKGEDLT----EEEDGGIIRRIRTRGEGYARPNDGAMVEVAL 174

  Fly   163 SEYLKKQMTAVEGQDSEELKNMLAENDKL-----VEEIFQHEDKDKN-----------GFISHDE 211
            ..|.|.::.     |..||...:.|.:.|     :||..|..:|.::           |.:..:.
Mouse   175 EGYHKDRLF-----DQRELCFEVGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKER 234

  Fly   212 FSGPKHDEL 220
            |..|.|.||
Mouse   235 FQIPPHAEL 243

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fkbp14NP_001246448.1 FKBP_C 37..130 CDD:278674 44/85 (52%)
EF-hand_7 140..212 CDD:290234 18/98 (18%)
EFh 141..212 CDD:298682 18/97 (19%)
Fkbp4NP_034349.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
FKBP_C 43..134 CDD:278674 43/84 (51%)
Interaction with tubulin. /evidence=ECO:0000250 267..400
TPR_11 274..349 CDD:290150
TPR repeat 274..301 CDD:276809
TPR repeat 306..348 CDD:276809
TPR_1 321..352 CDD:278916
TPR_11 322..384 CDD:290150
TPR repeat 353..381 CDD:276809
TPR_1 354..386 CDD:278916
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 428..458
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0545
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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