Protein Alignment Fkbp14 and FKBP9

DIOPT Version :9

• Sequence 1: NP_001246448.1
• Gene: Fkbp14 / 37449
• FlyBaseID: FBgn0010470
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_001271270.1
• Gene: FKBP9 / 11328
• HGNCID: 3725
• Length: 623
• Species: Homo sapiens
• Alignment Length: 355
• Identity: 87/355 - (24%)
• Similarity: 137/355 - (38%)
• Gaps: 162/355 - (45%)

  Fly     3 KSNLVISCLLL--------VAISNSLVRAQDLKVEVISTPEVCEQKSKNGDSLTMHYTGTLQADG 59
            :::||....||        ::|.|.:|            ||.||:.|::||.|..||.||| .||
Human   294 QASLVFDVALLDLHNPKDSISIENKVV------------PENCERISQSGDFLRYHYNGTL-LDG 345

  Fly    60 KKFDSSFDRDQPFTFQLGAGQVIKGWDQGLLNMCVGEKRKLTIPPQLGYGDQGAGN--------- 115
            ..||||:.|::.|...:|.|.||.|.|:|||.:|:||||::.:||.||||::|.||
Human   346 TLFDSSYSRNRTFDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGRGNIPGSAVLVF 410

  Fly   116 ----------------------------------------------------------------- 115
                                                                             
Human   411 DIHVIDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGS 475

  Fly   116 ----------------------VIPP---------------KATLLFDVELIN-----------I 132
                                  :|||               .|.|:||:||:.           |
Human   476 GQVVLGMDMGLREMCVGEKRTVIIPPHLGYGEAGVDGEVPGSAVLVFDIELLELVAGLPEGYMFI 540

  Fly   133 GNAPPTTNVFKEIDDNADKQLSREEVIVYVSEYLKKQMTAVEGQDSEELKNMLA---ENDKLVEE 194
            .|...:.|:|:|||.:.:.::..||    .|||:..|:.:.:|:        ||   :.:.:|:.
Human   541 WNGEVSPNLFEEIDKDGNGEVLLEE----FSEYIHAQVASGKGK--------LAPGFDAELIVKN 593

  Fly   195 IFQHEDKDKNGFISHDEF----SGPKHDEL 220
            :|.::|::.:|.::.:||    ...|||||
Human   594 MFTNQDRNGDGKVTAEEFKLKDQEAKHDEL 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp14	NP_001246448.1	FKBP_C	37..130	CDD:278674	50/203 (25%)
		EF-hand_7	140..212	CDD:290234	18/74 (24%)
		EFh	141..212	CDD:298682	17/73 (23%)
FKBP9	NP_001271270.1	FKBP_C	47..191	CDD:278674
		FKBP_C	212..304	CDD:278674	2/9 (22%)
		FKBP_C	324..415	CDD:278674	42/91 (46%)
		FKBP_C	435..527	CDD:278674	8/91 (9%)
		EF-hand_7	548..612	CDD:290234	19/75 (25%)
		EFh	550..611	CDD:238008	17/72 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1507309at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820