Protein Alignment Sdc and SDC1

DIOPT Version :10

• Sequence 1: NP_001163238.2
• Gene: Sdc / 37447
• FlyBaseID: FBgn0010415
• Length: 495
• Species: Drosophila melanogaster
• Sequence 2: XP_005262677.1
• Gene: SDC1 / 6382
• HGNCID: 10658
• Length: 334
• Species: Homo sapiens
• Alignment Length: 491
• Identity: 103/491 - (20%)
• Similarity: 151/491 - (30%)
• Gaps: 209/491 - (42%)

  Fly    44 AASRPHDEIYIDDDSIEGSGGRG-GIHEDLEKD----PDYSGSGFGPDDEDAEPDQHSHSSHNTR 103
            |.|.||.|:     |:.|.|..| |..|.|::.    |....:...|:|:|...|
Human    14 APSLPHLEL-----SLGGGGAAGEGRAESLDESEAMIPQIVATNLPPEDQDGSGD---------- 63

  Fly   104 ISQSSNSGINSKHNSNENYGKNSKNSNSDLISSRFNNNNNHNQIDNSQNINLNPNNNHQTNSGTI 168
                          .::|:..:...:..|:..|:                 ..|:....|...|.
Human    64 --------------DSDNFSGSGAGALQDITLSQ-----------------QTPSTWKDTQLLTA 97

  Fly   169 IGSSTTANNNNNHNININSQNGIISGSGSDIGGHSTGINSIAAHTPTQTSSTIPTTSTSTPMPTT 233
            |.:|.                            ..||:.:.||.|.|..:...|....:..:|..
Human    98 IPTSP----------------------------EPTGLEATAASTSTLPAGEGPKEGEAVVLPEV 134

  Fly   234 TPTATT--------PASTTTAAATQISSFANSSSTTTTTLAPTIPAEPQQPLFPPFDKDLDTESS 290
            .|..|.        |..||....|.:      :||||.|.|       |:|......:|:
Human   135 EPGLTAREQEATPRPRETTQLPTTHL------ASTTTATTA-------QEPATSHPHRDM----- 181

  Fly   291 GDGIDADAEDDDEDDGDDKDYDYNKELDKEIDIDGPEPGHLPPVVHHNTVETG------HIPTTD 349
                                                :|||     |..:...|      |.|.|:
Human   182 ------------------------------------QPGH-----HETSTPAGPSQADLHTPHTE 205

  Fly   350 EIDVDGGDE------DDNGDSDIDGPRIGGNDGDITERGPGAGGSNVHELDPNTNVNSQPSDTKG 408
                |||..      :|...|.:                |.|.||...:....|:
Human   206 ----DGGPSATERAAEDGASSQL----------------PAAEGSGEQDFTFETS---------- 240

  Fly   409 IDHRPNGNEVVIMSEDDR-------------TSSFFSQPGILAAVIGGAVVGLLCAILVVMFIVY 460
                 ..|..|:..|.||             :.....:..:|..||.|.:|||:.|:.:|.|::|
Human   241 -----GENTAVVAVEPDRRNQSPVDQGATGASQGLLDRKEVLGGVIAGGLVGLIFAVCLVGFMLY 300

  Fly   461 RMRKKDEGSYALDEPKRSPAN-NSYAKNANNREFYA 495
            ||:|||||||:|:|||:  || .:|.|.....||||
Human   301 RMKKKDEGSYSLEEPKQ--ANGGAYQKPTKQEEFYA 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sdc	NP_001163238.2	Syndecan	429..493	CDD:460035	28/64 (44%)
SDC1	XP_005262677.1	Syndecan	269..330	CDD:460035	28/62 (45%)