DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sdc and sdc4

DIOPT Version :9

Sequence 1:	NP_001163238.2	Gene:	Sdc / 37447	FlyBaseID:	FBgn0010415	Length:	495	Species:	Drosophila melanogaster
Sequence 2:	NP_001041614.1	Gene:	sdc4 / 568593	ZFINID:	ZDB-GENE-061111-1	Length:	201	Species:	Danio rerio

Alignment Length:	218	Identity:	67/218 - (30%)
Similarity:	99/218 - (45%)	Gaps:	66/218 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   286 DTESSGDGIDADAE------DDDED--DGDDKDYDYNKELDKEIDIDGPEPGHLPPVVHHNTVET 342
            |.||||:..:.|.|      .||||  |.||:| ||:       |:.|                :
Zfish    32 DLESSGNSQNEDFEFTDLNQTDDEDGFDEDDED-DYD-------DMSG----------------S 72

  Fly   343 GHIPTTDEIDVDGGDEDDNGDSDIDGPRIGGNDGDITERGPGAGGSNVHE--LDPNTNVNSQPSD 405
            |.....|:|      ||:..::.|.           .::||.|....|.|  |..|..|..:.:.
Zfish    73 GFADVIDDI------EDEFVNNQIP-----------DDKGPFAPRPTVDENILVQNNEVFLRGAP 120

  Fly   406 TKGIDHRPNGNEVVIMSE--DDRTSSFFSQPGILAAVIGGAVVGLLCAILVVMFIVY---RMRKK 465
            .:.:|:..|    |:|:.  ||   |.|:...:|||||.|..|||:.|||:::.:|:   |::||
Zfish   121 NQDLDNHSN----VLMTHAGDD---SLFNNTEVLAAVIAGGAVGLVFAILLIILLVHFVLRIKKK 178

  Fly   466 DEGSYALDEP---KRSPANNSYA 485
            |||||.|.:.   |::|....||
Zfish   179 DEGSYDLGKTPIYKKAPTTEIYA 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sdc	NP_001163238.2	Syndecan	429..493	CDD:279386	28/63 (44%)
sdc4	NP_001041614.1	Syndecan	139..198	CDD:279386	26/58 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575146
Domainoid	1	1.000	62	1.000	Domainoid score	I10320
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1507361at2759
OrthoFinder	1	1.000	-	-		FOG0003556
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10915
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4983
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.070