DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Acox57D-d and Gcdh

DIOPT Version :9

Sequence 1:NP_523803.1 Gene:Acox57D-d / 37446 FlyBaseID:FBgn0034629 Length:677 Species:Drosophila melanogaster
Sequence 2:NP_001102366.1 Gene:Gcdh / 364975 RGDID:1308829 Length:447 Species:Rattus norvegicus


Alignment Length:374 Identity:77/374 - (20%)
Similarity:130/374 - (34%) Gaps:111/374 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   118 HPIATHITMFVDVIKGQGTAEQVEKWGKAAENCNIIGTYAQTELAHGTNVRGLATRADFDPKTDE 182
            |||.|:           |:.||.:|:........::|.:..||..||::...:.|||..:|....
  Rat   159 HPIYTY-----------GSEEQRQKYLPRLAKGELLGCFGLTEPNHGSDPGSMETRARHNPSNKS 212

  Fly   183 FVLNTPNLEAYKWWPGGLGHTANHAMVVAQLYIADVHHGVQMFIVPLRDSET-------HMPLPG 240
            :.|:     ..|.|             :....:||      :|:|..|..:.       ...:.|
  Rat   213 YTLS-----GTKTW-------------ITNSPVAD------LFVVWARCEDNCIRGFLLEKGMRG 253

  Fly   241 VDIGEIGKKLGMASVNQGFLGLNHVRIPRTNMLMKFAKVERDGTFKASPASRINYLTMVYTRCLI 305
            :....|..|..:.:...|.:.::.|.:|..|:|...:.:       |.|..           ||.
  Rat   254 LSAPRIEGKFSLRASATGMIIMDSVEVPEENVLPNVSSL-------AGPFG-----------CLN 300

  Fly   306 VSQNSTL--LLAAATI----ATRYSAVRRQ--SPIEPNQ-PEPQIIDHVTQRLKLFPEIATGIAY 361
            .::....  :|.||..    |.:|:..|.|  .|:..|| .:.::.|.:|       ||..|:  
  Rat   301 TARYGITWGVLGAAEFCLHTARQYALDRIQFGVPLARNQLVQKKLADMLT-------EITLGL-- 356

  Fly   362 HLATEYMWEMYAQTVQEANNGKFERLPDMHILSCALKVLCTTDGCAG----IEKLRLSTGGHGYL 422
            |...:                 ..||.|....:..:..|...:.|..    ..:.|...||:|  
  Rat   357 HACLQ-----------------LGRLKDQDKATPEMVSLLKRNNCGKALDIARQARDILGGNG-- 402

  Fly   423 IAANLSNIYG------NAVAAYTYEGENTVLLLQIGRALVKAWASFVDK 465
                :|:.|.      |..|..||||.:.:..|.:|||:....|..|:|
  Rat   403 ----ISDEYHVIRHAMNLEAVNTYEGTHDIHALILGRAITGIQAFTVEK 447

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Acox57D-dNP_523803.1 ACAD 14..653 CDD:299127 77/374 (21%)
PLN02443 16..677 CDD:178062 77/374 (21%)
GcdhNP_001102366.1 GCD 57..443 CDD:173840 74/368 (20%)
CaiA 69..443 CDD:224871 74/368 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1960
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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