DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Acox57D-d and CG9527

DIOPT Version :9

Sequence 1:	NP_523803.1	Gene:	Acox57D-d / 37446	FlyBaseID:	FBgn0034629	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_001137800.1	Gene:	CG9527 / 33898	FlyBaseID:	FBgn0031813	Length:	724	Species:	Drosophila melanogaster

Alignment Length:	741	Identity:	199/741 - (26%)
Similarity:	325/741 - (43%)	Gaps:	127/741 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KNLIPSTVNPDLQKERAAAEFHVEEFSAWWHGGQDKLKKKREIEKAIFSDLEDGYGLNHEYMSHE 69
            |.:.|...:..|::.|..|.|..:..:.... |:|.::.|.::           :....::..::
  Fly    43 KRIFPDFRSGPLEEYRERASFCYKRMNVVLE-GEDHIRLKHKV-----------WQWMEQHPDYQ 95

  Fly    70 EVYNSTVKKVAEAAVKLKALQNKLNPGGTDIWPGGLFNAQSFGLFPANHPIATHIT------MFV 128
            ....|.:::..|.|.|.:.|..:....|.:.:.|......:||....::..:|.:.      ||.
  Fly    96 REPGSDLERTREMANKRQHLLWEQQFYGVNEYLGTPHLLLAFGQAIFSYDFSTSVKFGLSTGMFP 160

  Fly   129 DVIKGQGTAEQVEKWGKAAENCNIIGTYAQTELAHGTNVRGLATRADFDPKTDEFVLNTPNLEAY 193
            ..:...|:....:...|.|:| .|:|.||.||::||||..|:.|||.:|.|..||:::||:.||.
  Fly   161 STLVSNGSGRLGKYVAKIADN-RILGAYALTEISHGTNALGMRTRATYDVKRQEFIIHTPDFEAA 224

  Fly   194 KWWPGGLGHTANHAMVVAQLYIA-DVHHGVQMFIVPLRDSETHMPLPGVDIGEIGKKLGMASVNQ 257
            |.|.|.||.|..||:|.||||:. |.|.|:|.|:||:||..|.:|.|||.:|::|:|:|:..::.
  Fly   225 KCWVGNLGKTCTHAIVYAQLYVPDDKHQGLQAFLVPIRDERTLLPFPGVTVGDMGEKIGLNGIDN 289

  Fly   258 GFLGLNHVRIPRTNMLMKFAKVERDGTFK---------------ASPASRINYLTMVYTRCLIVS 307
            ||:..|..|||:.|:|.|...::..|.:.               |....|:|...:.|
  Fly   290 GFVMFNQYRIPKANLLSKTGDIDAQGNYTSKIKDERKRLGASLGALSVGRVNITAITY------- 347

  Fly   308 QNSTLLLAAATIATRYSAVRRQSPIEPNQPEPQIIDHVTQRLKLFPEIATGIAYHLATEYMW--- 369
               ..|..|.||||||:|.|||.....:..|..:|::.:|:.:|.|.:||.||..:||  :|
  Fly   348 ---VALSKAVTIATRYAASRRQFGPTNSPAEWPVIEYQSQQYRLIPHLATTIALRVAT--LWIGK 407

  Fly   370 -----EMYAQTVQEANNGKFERLPDMHILSCALKVLCTTDGCAGIEKLRLSTGGHGYLIAANLSN 429
                 .|...|.::.:....|    :|.:|.|||.:.|.....||::.|.:.||||||.::.|..
  Fly   408 ENVDLTMKGFTGEDTSQAGME----IHAISSALKPVATWAARDGIQECREACGGHGYLKSSGLGE 468

  Fly   430 IYGNAVAAYTYEGENTVLLLQIGRALVKAW---ASFVDKKPL-SASY-----------------S 473
            :..:..|..||||||..|:.|....|:...   |.||...|| :.|:                 :
  Fly   469 LRNDNDANCTYEGENNTLIQQASNWLISLQRNNADFVAVSPLETVSFLKDMDTILQSKGQERTPA 533

  Fly   474 YFASSMQLKEFPKWDDSWQCIIKALQYTAAHKTRIAFENLANRMASGQSQGVAANNT--GIELTR 536
            .....:.|.....|...||                 .:....|:...|.:|..|..|  .|::..
  Fly   534 EVLDPLNLLNALNWLTVWQ-----------------LDTTVKRVEEQQREGKDAFETRNNIQVFA 581

  Fly   537 AAEL---HGRQFVCQTFLEQITGA--KAQKRSPALNKILENVLELFLVQTVLNNLNDILR--FIK 594
            |.:|   :|.:.:...|.:.:.|.  .|:|      |:|:.||..:....|........|  :.:
  Fly   582 AQKLSIIYGERTIYYVFYKFVIGLPDSAEK------KVLQQVLSFYGAHLVTKYSAAFYRGGYFR 640

  Fly   595 LSDADLRSLQKRLEDSLAQFRPNAVAICDGFEFHDRVLNSVLGSYDGNVYPRLFDSAKRSTMNQK 659
            .:...|...::.:...|...:..|:|:.|.....|.:|||.||..|||||..|    :|:.::..
  Fly   641 ENSNQLELYEQGILALLPLLKNEAIALVDAIAPTDFILNSPLGMSDGNVYQHL----QRTLVSTP 701

  Fly   660 PV--------QTSFETYLKPLMKAKL 677
            .|        ..:::.|||   :|||
  Fly   702 GVYERPHWWRDVTYKDYLK---RAKL 724

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acox57D-d	NP_523803.1	ACAD	14..653	CDD:299127	189/698 (27%)
Acox57D-d	NP_523803.1	PLN02443	16..677	CDD:178062	195/728 (27%)
CG9527	NP_001137800.1	ACAD	52..694	CDD:299127	189/697 (27%)
CG9527	NP_001137800.1	PLN02312	56..682	CDD:215178	180/677 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460798
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840