DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Acox57D-d and Acoxl

DIOPT Version :9

Sequence 1:	NP_523803.1	Gene:	Acox57D-d / 37446	FlyBaseID:	FBgn0034629	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	XP_017447070.1	Gene:	Acoxl / 296138	RGDID:	1306814	Length:	656	Species:	Rattus norvegicus

Alignment Length:	612	Identity:	154/612 - (25%)
Similarity:	248/612 - (40%)	Gaps:	118/612 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 KREIEKAIFSD--LEDGYGLNHEYMSHEEVYNSTVKKVAEAAVKLKALQNKLNPGGTDIWPGGLF 106
            |.|:.:|:.|.  .:..|.|:.:.|  .::.|..||.|....:..:.||::......       |
  Rat    27 KNELRRALESSPLFQPRYDLSLDEM--RDLTNQRVKFVLSLPLLKRVLQDQEEKRNN-------F 82

  Fly   107 NAQSFGLFPANHPIATHITMFVDV----------------IKGQGTAEQVEKWGKAAENCNIIGT 155
            .:|||        :...:...|||                :...|:.|.|.||.:..:.....|.
  Rat    83 ISQSF--------VLGEVLCMVDVSMSIKCGVIFLLFGGAVNNLGSPEHVIKWFRPLKEQKYTGM 139

  Fly   156 YAQTELAHGTNVRGLATRADFDPKTDEFVLNTPNLEAYKWWPGGLGHTANHAMVVAQLYIADVHH 220
            :|.||..||:|:||:.|.|.||..:.|||::.|...|.|.:.|...| .|:|.|.|||.|.....
  Rat   140 FAMTEKGHGSNIRGIQTEATFDCDSQEFVIDMPCENAQKMYIGNAMH-GNYAAVFAQLIIEGKSQ 203

  Fly   221 GVQMFIVPLRDSETHMPLPGVDIGEIGKKLGMASVNQGFLGLNHVRIPRTNMLMKFAKVERDGTF 285
            |...||||:||...:: .|||...::..|.|:..|:.|.|..:.|||||.|||.|...|..||.:
  Rat   204 GPHCFIVPIRDENGNL-YPGVTAIDMMYKEGLNGVDNGILIFDKVRIPRENMLDKLGSVTPDGQY 267

  Fly   286 KA---SPASRINYLTMVYT--RCLIVSQNSTLLLAAATIATRYSAVRRQ-SPIEPNQPEPQIIDH 344
            .:   |.::|.|.:..:.|  |..:..|....:.....||.|||..||| .|  ..:.|.:||:|
  Rat   268 HSPIQSKSARFNAMLAILTPSRLAVTFQAMGAMKLGLMIAIRYSHSRRQFGP--KGKEEVKIIEH 330

  Fly   345 VTQRLKLFPEIATGIAYHLATEYMWEMYAQTV---QEANNGKFERLPDMHILSCALKVLCTTDGC 406
            ..|.|:|...:||.:|....:.:...:..:.:   :|..|.:     .:..|...||...|.:..
  Rat   331 QMQALRLMSHLATALALTFTSRHAGHILDEDILQGRELINRR-----SLQALMAGLKAYSTWETV 390

  Fly   407 AGIEKLRLSTGGHGYLIAANLSNIYGNAVAAYTYEGENTVLLLQIGRALVKAWASFVDKKP---- 467
            ..::..|..|||.||::...||.:..:.....|:||:|.|:|..:.|.|:..::....|.|
  Rat   391 RCLQDCRECTGGMGYMMENRLSGLKCDTDVFVTFEGDNVVMLQVVARELLAQYSKQHKKNPFLGM 455

  Fly   468 -----------LSASY-----------SYFASSMQLKE----------------------FPKWD 488
                       |..|:           ::...::..:|                      |..|:
  Rat   456 IQNWTETAMDKLRTSFLVFNTDTVGHLAFLLKAVNFRERVLQRSLVSRIYYKVVTEKGDFFRAWN 520

  Fly   489 DSWQCIIKALQYTAAHKTRIAFE--NLANRMASGQSQGVAANNTGIELTRAAELHGRQFVCQT-- 549
               .|:...:..:.||..|:|.|  .||.|....:.....       |.:...|:|.:.:.|.
  Rat   521 ---SCMHHVISLSLAHVHRVALEQFTLAVRQCPNREDQAL-------LMKFCLLYGTKLLFQERG 575

  Fly   550 -FLEQ--ITGAKAQKRSPALNKILENV 573
             :||.  :|.|.:.:....|..:.|:|
  Rat   576 WYLEHKYLTPAASMRIRAQLLNLCESV 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acox57D-d	NP_523803.1	ACAD	14..653	CDD:299127	154/612 (25%)
Acox57D-d	NP_523803.1	PLN02443	16..677	CDD:178062	154/612 (25%)
Acoxl	XP_017447070.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810