DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Acox57D-d and Acad9

DIOPT Version :9

Sequence 1:	NP_523803.1	Gene:	Acox57D-d / 37446	FlyBaseID:	FBgn0034629	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_861433.2	Gene:	Acad9 / 294973	RGDID:	727973	Length:	625	Species:	Rattus norvegicus

Alignment Length:	600	Identity:	124/600 - (20%)
Similarity:	204/600 - (34%)	Gaps:	141/600 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 EIEKAIFSDLEDGYGLNHEYMSHEEVYNSTV----KKVAEAAVKLKALQNKLNPGGTDIWPGGLF 106
            |:.:...|::....|...::. :|||.:..:    |..|:...|||:|              |||
  Rat    62 EVSQEELSEINQFVGPLEKFF-NEEVDSRKIDQEGKIPADTLAKLKSL--------------GLF 111

  Fly   107 NAQ------SFGLFPANH---------------PIATHITMFVDVIKGQGTAEQVEKWGKAAENC 150
            ..|      ..||....:               .:|.|..:.:..|...|..||..|:.....:.
  Rat   112 GIQVPEEYGGLGLSNTMYARLGEIISMDASITVTLAAHQAIGLKGIILVGNEEQKAKYLPKLSSG 176

  Fly   151 NIIGTYAQTELAHGTNVRGLATRADFDPKTDEFVLNTPNLEAYKWW--PGGLGHTANHAMVVAQL 213
            ..|..:..||.|.|::...:.|||........||||     ..|.|  .|||   ||...|.|:.
  Rat   177 EHIAAFCLTEPASGSDAASIQTRATLSEDKKYFVLN-----GSKVWITNGGL---ANIFTVFAKT 233

  Fly   214 YIAD----VHHGVQMFIVPLRDSETHMPLPGVDIGEIGKKLGMASVNQGFLGLNHVRIPRTNMLM 274
            .:.|    :...:..|||. ||      ..|:..|:...|||:...|...:...:.|:|..|:|
  Rat   234 EVVDSDGSIKDKMTAFIVE-RD------FGGITNGKPEDKLGIRGSNTCEVHFENTRVPVENVL- 290

  Fly   275 KFAKVERDGTFKASPASRINYLTMVYTRCLIVSQNSTLLLAAATIATRYSAVRRQSPIEPNQPEP 339
                .|..|.||.:    :|.|..  .|..:.|..:.:|.........|:..|:|
  Rat   291 ----GEVGGGFKVA----MNILNS--GRFSMGSAVAGMLKKLIEQTAEYACTRKQ---------- 335

  Fly   340 QIIDHVTQRLKLFPEIATGIAYHLATEYMWEMYAQTVQEANNGKFER--LPDMHILSCALKVLCT 402
                 ..:.|..|..|....|......|:.|..|.    ..:|..::  .||..|.:..:||..:
  Rat   336 -----FNRNLSEFGLIQEKFALMAQKAYVMESMAY----LTSGMLDQPGFPDCSIEAAMVKVFSS 391

  Fly   403 TDGCAGIEKLRLSTGGHGYLIAANLSNIYGNAVAAYTYEGENTVLLLQI--------GRALVKAW 459
            ......:.:.....||.||:.......:..:|.....:||.|.:|.|.|        ||.|
  Rat   392 EAAWQCVSEALQILGGSGYMKDYPYERMLRDARILLIFEGTNEILRLFIALTGLQHAGRIL---- 452

  Fly   460 ASFVDKKPLSASYSYFASSMQLKEFPKWDDSWQCIIKALQYTAAHKTRIAFENLANRMASGQSQG 524
                              :.::||....:      :..:..|...|.|   ::|...:..|.|..
  Rat   453 ------------------TSRIKELKSGN------VTTVMETIGRKLR---DSLGRTVDLGLSSN 490

  Fly   525 VAA-----NNTGIELTRAAELHGRQFVCQTFLEQITGAKAQKRSPALNKILENVLELFLVQTVLN 584
            :|.     .::..:|.......||  ..:|.|.:. |....:....|.::...::.|:.:..||:
  Rat   491 IAVVHPSLGDSANKLEENVHYFGR--TVETLLLRF-GKTIVEEQLVLKRVANILINLYGMTAVLS 552

  Fly   585 NLNDILRFIKLSDAD 599
            ..:..:| |.|.:.|
  Rat   553 RASRSIR-IGLKNHD 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acox57D-d	NP_523803.1	ACAD	14..653	CDD:299127	123/599 (21%)
Acox57D-d	NP_523803.1	PLN02443	16..677	CDD:178062	123/599 (21%)
Acad9	NP_861433.2	VLCAD	42..449	CDD:173850	98/446 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910