DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Acox57D-p and Acox3

DIOPT Version :9

Sequence 1:	NP_001286677.1	Gene:	Acox57D-p / 37445	FlyBaseID:	FBgn0034628	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	XP_006504259.1	Gene:	Acox3 / 80911	MGIID:	1933156	Length:	755	Species:	Mus musculus

Alignment Length:	696	Identity:	195/696 - (28%)
Similarity:	316/696 - (45%)	Gaps:	126/696 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LQKERDAASFNSEEFAAWWAGGEEVLKFNRGVREYMEK----------DVDLSEMLQLQNKTHEE 70
            |...|..|||||.|...:| .|::|:.|.:.:...:|.          |:.|.::.:|.....:.
Mouse    21 LSAYRARASFNSGELLLFW-DGQDVIHFKKTIFSTLENDPLFARSYGADLPLEKLRELNFLRCKR 84

  Fly    71 IIEFSTRGAIEGAKKLRRLQEERNPGGDVYWPN---LYDAQVMWGLVPGGNPFGVMYVMLVKALQ 132
            :.|:       |..|:..|.  :||...:...|   :||    |.|   .|.. |:::::.....
Mouse    85 VFEY-------GFFKVEELL--KNPLKILVLINCLGMYD----WSL---ANKC-VLHMLVFGTTV 132

  Fly   133 AQCTPEQYEEFGKRVELFEICGTYAQTELGHGTYLRGLETRADFDRKTDQFVLNTPNISSYKWWP 197
            .....|::.::.:::...||.|.:|.|||.||:..:.:.|.|.:|..|.:|:|::|:..:.|:|.
Mouse   133 FVSGSEKHFKYLEKIYSLEIFGCFALTELSHGSNTKAMRTTAHYDPDTQEFILHSPDFEAAKFWV 197

  Fly   198 GGLGHSSNHCLVMAQLYI-DGDCKGPHMFFIQVRDEDTHEPLPGVHIGDIGKKMGFIGVNNGFLG 261
            |.||.::.|.:|.||||: ||.|.|.|.|.:|:||..|..|:.||.:||||||:|..|::|||..
Mouse   198 GNLGKTATHAVVFAQLYMPDGQCHGLHSFLVQIRDTKTLLPMTGVMVGDIGKKLGQNGLDNGFAM 262

  Fly   262 LKNVRIPRTRMLMRHAQVKADGSYVSSPTNVLTYFAMVRT------------RCVIAKNNAVMLA 314
            ...|||||..:|.|...:.::|:| :||      |..||.            |..|...:.|.|.
Mouse   263 FNKVRIPRQNLLDRTGNITSEGTY-NSP------FKDVRQRLGASLGSLSSGRISIISMSVVNLK 320

  Fly   315 SAATIATRYSAVRRQSPINPNEREP-QIMDHVTQQMKLFPEIATSVAY----------------- 361
            .|.:||.|:||.|.|  ..|.::|. .::::..||.::.|.:|.:.|.
Mouse   321 LAVSIAIRFSATRCQ--FGPTDKEEIPVLEYPLQQWRILPYLAAAYALDHFSKTIFMDLIEVQSA 383

  Fly   362 RKAGDYLWNLYDVTIEDIENGKYERLPELHSLSCALKVTCSMDSASGVEKLRLACGGHGFLTSSN 426
            |..||:       :.:..|.|:     |:|:|:.|.|...|..:..|:::.|.||||||:|..:.
Mouse   384 RLRGDH-------SDQQAELGR-----EIHALASAGKPLASWTAQRGIQECREACGGHGYLAMNR 436

  Fly   427 MSSIYVSATAACTYEGENTVLLLQIGRFLMKTWRAALTGAPLPPTVRYLAEVQKNPEF------- 484
            ...:.......|||||:|.|||.|...:|:     :|...||.....:.:.: |..:|
Mouse   437 FGDLRNDNDPNCTYEGDNNVLLQQTSNYLL-----SLLEPPLQDGAHFTSPL-KTVDFLEAYPGI 495

  Fly   485 ------GTWTGSWENMVKAMQYAAANRTQLAF-------RSLSKRMSRGETEANAANHTGIEFTQ 536
                  |:....|.:....:   ||.|..:.:       |...::.||| ::..|.|::.:...:
Mouse   496 LGQKFLGSSKADWMDSAAPL---AAYRWLVCYLLQESHRRYCQEKKSRG-SDFEARNNSQVYGCR 556

  Fly   537 AAELHGRAF----VFSAFYEAVTGPQSKTRSANFNRVLENLLELYLVKETLNQMGHLLR--FINL 595
            ...|   ||    |...|:|.:   .|...|.:...||..|..||.:......|..|.|  :|:.
Mouse   557 PLAL---AFMELTVMQRFHEHI---HSSGLSPSLRTVLGRLSTLYGLWCLSQHMALLYRGGYISG 615

  Fly   596 TDTDLSGLQDRLETVLTKLRPDAVAIVDGFDFSDLQLNSTLGSYDG 641
            ..|. ..::|.:.|:..:|:.||||:||....||..|||.:...||
Mouse   616 EQTG-RAMEDAILTLCEQLKDDAVALVDVIAPSDFVLNSPIAKADG 660

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acox57D-p	NP_001286677.1	ACAD	14..653	CDD:299127	195/696 (28%)
Acox57D-p	NP_001286677.1	PLN02443	16..677	CDD:178062	195/696 (28%)
Acox3	XP_006504259.1	AXO	19..663	CDD:173839	195/696 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810