Protein Alignment Acox57D-p and ACOX1

DIOPT Version :10

• Sequence 1: NP_523802.1
• Gene: Acox57D-p / 37445
• FlyBaseID: FBgn0034628
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_004026.2
• Gene: ACOX1 / 51
• HGNCID: 119
• Length: 660
• Species: Homo sapiens
• Alignment Length: 670
• Identity: 264/670 - (39%)
• Similarity: 372/670 - (55%)
• Gaps: 36/670 - (5%)

  Fly    12 VNPDLQKERDAASFNSEEFAAWWAGGEEVLKFNRGVREYMEKDVDLSEMLQLQNKTHEEIIEFST 76
            :||||::|||:||||.|.......|..|..:..|.:...:..|.|.... .|...|..:..|.:.
Human     1 MNPDLRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDPDFQHE-DLNFLTRSQRYEVAV 64

  Fly    77 RGAIEGAKKLRRLQEERNPGGDVYWPNLYDA-QVMW--GLVPGG--NPFGVMYVMLVKALQAQCT 136
            |.:....||:|..             .:.|. ::||  ..|..|  .|..:...|.:..|..|.|
Human    65 RKSAIMVKKMREF-------------GIADPDEIMWFKNFVHRGRPEPLDLHLGMFLPTLLHQAT 116

  Fly   137 PEQYEEFGKRVELFEICGTYAQTELGHGTYLRGLETRADFDRKTDQFVLNTPNISSYKWWPGGLG 201
            .||.|.|.......||.|||||||:||||:||||||.|.:|.:|.:|:||:|.::|.||||||||
Human   117 AEQQERFFMPAWNLEIIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVTSIKWWPGGLG 181

  Fly   202 HSSNHCLVMAQLYIDGDCKGPHMFFIQVRDEDTHEPLPGVHIGDIGKKMGFIGVNNGFLGLKNVR 266
            .:|||.:|:|||...|.|.|.|.|.:.:|:..||:||||:.:||||.|.|:..::||:|.:.|.|
Human   182 KTSNHAIVLAQLITKGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPKFGYDEIDNGYLKMDNHR 246

  Fly   267 IPRTRMLMRHAQVKADGSYVSSPTNVLTYFAMVRTRCVIAKNNAVMLASAATIATRYSAVRRQSP 331
            |||..|||::||||.||:||...:|.|||..||..|..:....|..|:.|.|||.||||||.||.
Human   247 IPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARALSKACTIAIRYSAVRHQSE 311

  Fly   332 INPNEREPQIMDHVTQQMKLFPEIATSVAYRKAGDYLWNLYDVTIEDIENGKYERLPELHSLSCA 396
            |.|.|.||||:|..|||.||||.:||:.|::..|.|:...|....|.|..|....|||||:|:..
Human   312 IKPGEPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGIGQGDLSELPELHALTAG 376

  Fly   397 LKVTCSMDSASGVEKLRLACGGHGFLTSSNMSSIYVSATAACTYEGENTVLLLQIGRFLMKTWRA 461
            ||...|..:.:|:|..|:||||||:...|.:.:|||:.|.:||:||||||::||..|||||::..
Human   377 LKAFTSWTANTGIEACRMACGGHGYSHCSGLPNIYVNFTPSCTFEGENTVMMLQTARFLMKSYDQ 441

  Fly   462 ALTGAPLPPTVRYLAEVQKN----PEFGTW-----TGSWENMVKAMQYAAANRTQLAFRSLSKRM 517
            ..:|..:...|.||.::...    .:...|     ..|.|::.:|.:..||...::|.::|.|.:
Human   442 VHSGKLVCGMVSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKLRAARLVEIAAKNLQKEV 506

  Fly   518 SRGETEANAANHTGIEFTQAAELHGRAFVFSAFYEAVTGPQSKTRSANFNRVLENLLELYLVKET 582
            ...:::..|.|.|.::..:|:|.|....|...|.|.:...|.|...|    ||.:|..||.:...
Human   507 IHRKSKEVAWNLTSVDLVRASEAHCHYVVVKLFSEKLLKIQDKAIQA----VLRSLCLLYSLYGI 567

  Fly   583 LNQMGHLLRFINLTDTDLSGLQDRLETVLTKLRPDAVAIVDGFDFSDLQLNSTLGSYDGNAYERI 647
            ....|..|:...:|:..::.:..|::.:||.:|.||||:||.|||.|:.|.|.||.||||.||.:
Human   568 SQNAGDFLQGSIMTEPQITQVNQRVKELLTLIRSDAVALVDAFDFQDVTLGSVLGRYDGNVYENL 632

  Fly   648 FDAALKNPMNQKAVPKYFHE 667
            |:.|..:|:|:..|    ||
Human   633 FEWAKNSPLNKAEV----HE 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acox57D-p	NP_523802.1	ACAD	14..653	CDD:447864	258/652 (40%)
ACOX1	NP_004026.2	AXO	3..637	CDD:173839	257/651 (39%)