Protein Alignment Acox57D-p and ACADVL

DIOPT Version :10

• Sequence 1: NP_523802.1
• Gene: Acox57D-p / 37445
• FlyBaseID: FBgn0034628
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001257376.1
• Gene: ACADVL / 37
• HGNCID: 92
• Length: 678
• Species: Homo sapiens
• Alignment Length: 630
• Identity: 120/630 - (19%)
• Similarity: 203/630 - (32%)
• Gaps: 152/630 - (24%)

  Fly    15 DLQKERDAASFNSEEFAAWWAGG----EEVLKFNRGVREYMEKDVDLSEMLQLQNKTHEEIIEFS 75
            |....:..|...|:.||.....|    ::|..:...:.|  |:...|.|:::..::..||:.:.:
Human    81 DALTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNE--EQTQFLKELVEPVSRFFEEVNDPA 143

  Fly    76 TRGAIE--------GAKKLRR--LQEERNPGG----DVYWPNLYDAQVMWGLVPG-GNPFGVMYV 125
            ...|:|        |.|:|..  ||.....||    :..:..|.:...|..|  | |...|....
Human   144 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDL--GVGITLGAHQS 206

  Fly   126 MLVKALQAQCTPEQYEEFGKRVELFEICGTYAQTELGHGTYLRGLETRADFDRKTDQFVLNTPNI 190
            :..|.:....|..|.|::..::...|....:..||...|:....:.|.|........:.||
Human   207 IGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLN---- 267

  Fly   191 SSYKWW--PGGLGHSSNHCLVMAQLYIDGDCKGPHMFFIQVRDEDT----HEPLPGVHIGDIGKK 249
             ..|.|  .|||   ::...|.|:..:.....|      .|:::.|    .....|:..|...||
Human   268 -GSKLWISNGGL---ADIFTVFAKTPVTDPATG------AVKEKITAFVVERGFGGITHGPPEKK 322

  Fly   250 MGFIGVNNGFLGLKNVRIPRTRMLMRHAQVKADGSYVSSPTNVLTYFAMVRTRCVIAKNNAVMLA 314
            ||....|...:....||:|...:|   .:|   ||......::|              ||.....
Human   323 MGIKASNTAEVFFDGVRVPSENVL---GEV---GSGFKVAMHIL--------------NNGRFGM 367

  Fly   315 SAATIATRYSAVRRQSPINPNEREPQIMDHVTQ-------------------QMKLFPEIATSVA 360
            :||...|....:.:            .:||.|.                   :|.:...:..|:|
Human   368 AAALAGTMRGIIAK------------AVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMA 420

  Fly   361 YRKAGDYLWNLYDVTIEDIENGKYERLPELHSLSCALKVTCSMDSASGVEKLRLACGGHGFLTSS 425
            |..:.:......|..||       ..:.::.....|.|||         ::.....||.||:...
Human   421 YMVSANMDQGATDFQIE-------AAISKIFGSEAAWKVT---------DECIQIMGGMGFMKEP 469

  Fly   426 NMSSIYVSATAACTYEGENTVLLLQIGRFLMKTWRAALTGA-PLPPTVRYLAEVQKNPEFGTWTG 489
            .:..:.........:||.|.:|.|.:          ||.|. .....:..|....||| ||
Human   470 GVERVLRDLRIFRIFEGTNDILRLFV----------ALQGCMDKGKELSGLGSALKNP-FG---- 519

  Fly   490 SWENMVKAMQYAAANRTQLAFRSLSKRMSRGETEANAANHTGI---EFTQAAELHGRAFVFSAFY 551
                           ...|......|::.|.....:..:.:|:   |.:::.||..||  ...|.
Human   520 ---------------NAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRA--LEQFA 567

  Fly   552 EAVTGPQSKTRSANFN------RVLENLLELYLVKETLNQMGHLL 590
            ..|.....|.:....|      |:.:..::||.:...|::....|
Human   568 TVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSL 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acox57D-p	NP_523802.1	ACAD	14..653	CDD:447864	120/630 (19%)
ACADVL	NP_001257376.1	VLCAD	95..504	CDD:173850	93/484 (19%)