DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Acox57D-p and CG17544

DIOPT Version :9

Sequence 1:	NP_001286677.1	Gene:	Acox57D-p / 37445	FlyBaseID:	FBgn0034628	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_001163015.1	Gene:	CG17544 / 35213	FlyBaseID:	FBgn0032775	Length:	693	Species:	Drosophila melanogaster

Alignment Length:	576	Identity:	157/576 - (27%)
Similarity:	274/576 - (47%)	Gaps:	41/576 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 ALQAQCTPEQYEEFGKRVELFEICGTYAQTELGHGTYLRGLETRADFDRKTDQFVLNTPNISSYK 194
            |::|..| |:::::.:.....|:....|.|||.||:..:.:.|.|.:|..|.:||:|||:..:.|
  Fly   131 AIRAMGT-EKHQKYIEAAWNREVITCLAITELSHGSNTKSIRTTATYDPTTQEFVINTPDFEAAK 194

  Fly   195 WWPGGLGHSSNHCLVMAQLY-IDGDCKGPHMFFIQVRDEDTHEPLPGVHIGDIGKKMGFIGVNNG 258
            .|.|.||.::...:..|.|| .||...|.|.|.|.:||..|....|||.:||||:|.|..|::||
  Fly   195 CWVGNLGKTATVAMTFANLYTADGQNHGLHGFLIPIRDPKTLLSYPGVLVGDIGEKCGLNGIDNG 259

  Fly   259 FLGLKNVRIPRTRMLMRHAQVKADGSYVS---SPTNVL--TYFAMVRTRCVIAKNNAVMLASAAT 318
            |:...|.||||..:|.|.:.|..:|.|.|   .|..||  ...:....|..|.:.:|..|.|||.
  Fly   260 FVVFTNYRIPRDNLLNRTSDVTPEGVYESVFTEPGKVLGAALESFSAGRIGIMQESANTLCSAAV 324

  Fly   319 IATRYSAVRRQSPINPNEREPQIMDHVTQQMKLFPEIATSVAYRKAGDYLWNLYDVTI---EDIE 380
            ||.||||||:|.....:..|..|:::...|.::||.:|.:...:.|.:.|.:.|...|   :...
  Fly   325 IAVRYSAVRKQFGPERHGEEMAILEYQLHQYRIFPYLAAACVQKIATEELTSTYMEIIARSQADS 389

  Fly   381 NG---KYERLPELHSLSCALKVTCSMDSASGVEKLRLACGGHGFLTSSNMSSIYVSATAACTYEG 442
            ||   ..:...|:|:|..:.|...:..:...:::.|.||||||:|.::.:..:.......|||||
  Fly   390 NGFDVLTQNAAEIHALISSSKPLITWAARDAIQEAREACGGHGYLQAAKLGQMRTDHDPLCTYEG 454

  Fly   443 ENTVLLLQIGRFLMKTWRAALTGAPLPP-----------TVRYLAEVQKNPEFGTWTGSWENMVK 496
            :|.||..|...:|::.|.|.....|:..           .:.|.:..||.|     ..||:..::
  Fly   455 DNNVLGQQASNWLLRQWSAKELETPIGSVKFLERRSELLALNYASLAQKTP-----IASWQFSLR 514

  Fly   497 AMQYAAANRTQLAFRSLSKRMSRGETEANAANHTGIEFTQAAEL-HGRAFVFSAFYEAVTGPQSK 560
            ..::...:........:..:::.|.::..|.|::.:...:...| :...:..:.:.:.|:....:
  Fly   515 CYEWLLCHLMAKTTAHIEGQLAAGSSKFEARNNSQVAGARELSLAYAEYYALTRYVDHVSTLTVE 579

  Fly   561 TRSANFNRVLENLLELYLVKETLNQMGHLLRFINLTDTDLSGLQDRLETVLTKLRPDAVAIVDGF 625
            ...|:..|:|.::..::|:::.:... ::..|....|...:..|..|::.| ||:..||::.|..
  Fly   580 APYASVLRLLFDVYAMWLLEKHMTTF-YVGGFAAGRDFSAAVRQLLLDSCL-KLKDVAVSVADAI 642

  Fly   626 DFSDLQLNSTLGSYDGNAYERIFDAALKNPM--NQKAV--PKYFHEILRPFMKSNI 677
            ...|..|||.:...||..||.     |:|..  |:.|.  |.::.:::.|..:|.:
  Fly   643 SPPDFALNSVIARADGLLYEN-----LQNEFMTNEGAFQRPSWWRDVIIPQAQSKL 693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acox57D-p	NP_001286677.1	ACAD	14..653	CDD:299127	150/546 (27%)
Acox57D-p	NP_001286677.1	PLN02443	16..677	CDD:178062	157/574 (27%)
CG17544	NP_001163015.1	AXO	16..670	CDD:173839	152/551 (28%)
CG17544	NP_001163015.1	PLN02443	18..687	CDD:178062	155/568 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910