DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Acox57D-p and CG9527

DIOPT Version :9

Sequence 1:	NP_001286677.1	Gene:	Acox57D-p / 37445	FlyBaseID:	FBgn0034628	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_001137800.1	Gene:	CG9527 / 33898	FlyBaseID:	FBgn0031813	Length:	724	Species:	Drosophila melanogaster

Alignment Length:	721	Identity:	193/721 - (26%)
Similarity:	308/721 - (42%)	Gaps:	136/721 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VIPTTVNPDLQKERDAASFNSEEFAAWWAGGEEVLKFNRGVREYMEKDVDLSEMLQLQNKTHEEI 71
            :.|...:..|::.|:.|||..:.... ...||:.::....|.::||:..|...
  Fly    45 IFPDFRSGPLEEYRERASFCYKRMNV-VLEGEDHIRLKHKVWQWMEQHPDYQR------------ 96

  Fly    72 IEFSTRGAIEGAKKLRRLQEERNPGGDVYW-------------PNL----------YD--AQVMW 111
                     |....|.|.:|..|....:.|             |:|          ||  ..|.:
  Fly    97 ---------EPGSDLERTREMANKRQHLLWEQQFYGVNEYLGTPHLLLAFGQAIFSYDFSTSVKF 152

  Fly   112 GLVPGGNPFGVMYVMLVKALQAQCTPEQYEEFGKRVELF---EICGTYAQTELGHGTYLRGLETR 173
            ||..|..|             :..........||.|...   .|.|.||.||:.|||...|:.||
  Fly   153 GLSTGMFP-------------STLVSNGSGRLGKYVAKIADNRILGAYALTEISHGTNALGMRTR 204

  Fly   174 ADFDRKTDQFVLNTPNISSYKWWPGGLGHSSNHCLVMAQLYI-DGDCKGPHMFFIQVRDEDTHEP 237
            |.:|.|..:|:::||:..:.|.|.|.||.:..|.:|.||||: |...:|...|.:.:|||.|..|
  Fly   205 ATYDVKRQEFIIHTPDFEAAKCWVGNLGKTCTHAIVYAQLYVPDDKHQGLQAFLVPIRDERTLLP 269

  Fly   238 LPGVHIGDIGKKMGFIGVNNGFLGLKNVRIPRTRMLMRHAQVKADGSYVSSPTNV-----LTYFA 297
            .|||.:||:|:|:|..|::|||:.....|||:..:|.:...:.|.|:|.|...:.     .:..|
  Fly   270 FPGVTVGDMGEKIGLNGIDNGFVMFNQYRIPKANLLSKTGDIDAQGNYTSKIKDERKRLGASLGA 334

  Fly   298 MVRTRCVIAKNNAVMLASAATIATRYSAVRRQ-SPINPNEREPQIMDHVTQQMKLFPEIATSVAY 361
            :...|..|.....|.|:.|.||||||:|.||| .|.|.....| ::::.:||.:|.|.:||::|.
  Fly   335 LSVGRVNITAITYVALSKAVTIATRYAASRRQFGPTNSPAEWP-VIEYQSQQYRLIPHLATTIAL 398

  Fly   362 RKAGDYLW----NLYDVTI-----EDIENGKYERLPELHSLSCALKVTCSMDSASGVEKLRLACG 417
            |.|  .||    |: |:|:     ||......    |:|::|.|||...:..:..|:::.|.|||
  Fly   399 RVA--TLWIGKENV-DLTMKGFTGEDTSQAGM----EIHAISSALKPVATWAARDGIQECREACG 456

  Fly   418 GHGFLTSSNMSSIYVSATAACTYEGENTVLLLQIGRFLMKTWRAALTGAPLPP--TVRYLAEV-- 478
            |||:|.||.:..:.....|.|||||||..|:.|...:|:...|.......:.|  ||.:|.::
  Fly   457 GHGYLKSSGLGELRNDNDANCTYEGENNTLIQQASNWLISLQRNNADFVAVSPLETVSFLKDMDT 521

  Fly   479 -------QKNPEFGTWTGSWE-----NMVKAMQYAAANRTQLAFRSLSKRMSRGETEANAANHTG 531
                   ::.|.        |     |::.|:.:....:.....:.:.::...|:......|:..
  Fly   522 ILQSKGQERTPA--------EVLDPLNLLNALNWLTVWQLDTTVKRVEEQQREGKDAFETRNNIQ 578

  Fly   532 IEFTQAAE-LHGRAFVFSAFYEAVTG-PQSKTRSANFNRVLENLLELYLVKETLNQMGHLLR--- 591
            :...|... ::|...::..||:.|.| |.|..:     :||:.:|..|        ..||:.
  Fly   579 VFAAQKLSIIYGERTIYYVFYKFVIGLPDSAEK-----KVLQQVLSFY--------GAHLVTKYS 630

  Fly   592 -------FINLTDTDLSGLQDRLETVLTKLRPDAVAIVDGFDFSDLQLNSTLGSYDGNAYERIFD 649
                   :.......|...:..:..:|..|:.:|:|:||....:|..|||.||..|||.|:.:..
  Fly   631 AAFYRGGYFRENSNQLELYEQGILALLPLLKNEAIALVDAIAPTDFILNSPLGMSDGNVYQHLQR 695

  Fly   650 AALKNP 655
            ..:..|
  Fly   696 TLVSTP 701

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acox57D-p	NP_001286677.1	ACAD	14..653	CDD:299127	191/710 (27%)
Acox57D-p	NP_001286677.1	PLN02443	16..677	CDD:178062	192/712 (27%)
CG9527	NP_001137800.1	ACAD	52..694	CDD:299127	191/705 (27%)
CG9527	NP_001137800.1	PLN02312	56..682	CDD:215178	184/689 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460800
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840