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Protein Alignment Acox57D-p and GCDH

DIOPT Version :9

Sequence 1:	NP_001286677.1	Gene:	Acox57D-p / 37445	FlyBaseID:	FBgn0034628	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_000150.1	Gene:	GCDH / 2639	HGNCID:	4189	Length:	438	Species:	Homo sapiens

Alignment Length:	402	Identity:	77/402 - (19%)
Similarity:	136/402 - (33%)	Gaps:	133/402 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 AQVMWGL-------VPGG--NPFGVMYVMLVKALQAQCTPEQYEEFGKRVELFEICGTYAQTELG 162
            :.|.:||       |..|  :...|...:::..:.|..:.||.:::..::...|:.|.:..||..
Human   119 SSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGELLGCFGLTEPN 183

  Fly   163 HGTYLRGLETRADFDRKTDQFVLNTPNISSYKWWPGGLGHSSNHCLVMAQLYI------DGDCKG 221
            .|:....:||||.::.....:.||     ..|.|   :.:|.     ||.|::      ||..:|
Human   184 SGSDPSSMETRAHYNSSNKSYTLN-----GTKTW---ITNSP-----MADLFVVWARCEDGCIRG 235

  Fly   222 PHMFFIQVRDEDTHEPLPGVHIGDIGKKMGFIGVNNGFLGLKNVRIPRTRMLMRHAQVKADGSYV 286
               |.::       :.:.|:....|..|........|.:.:..|.:|...:|       ...|.:
Human   236 ---FLLE-------KGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVL-------PGASSL 283

  Fly   287 SSPTNVLTYFAMVRTRCVIAKNNA-------VMLASAATI--ATRYSAVRRQ--SPINPNER-EP 339
            ..|...|              |||       |:.||...:  |.:|:..|.|  .|:..|:. :.
Human   284 GGPFGCL--------------NNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQK 334

  Fly   340 QIMDHVTQ----------------QMKLFPEIATSVAYRKAGDYLWNLYDVTIEDIENGKYERLP 388
            ::.|.:|:                |.|..||:.:.:.....|..|         ||
Human   335 KLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGKAL---------DI--------- 381

  Fly   389 ELHSLSCALKVTCSMDSASGVEKLRLACGGHGFLTSSNMSSIYVSATAACTYEGENTVLLLQIGR 453
                                ..:.|...||:|.....::....::..|..||||.:.:..|.:||
Human   382 --------------------ARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALILGR 426

  Fly   454 FLMKTWRAALTG 465
                    |:||
Human   427 --------AITG 430

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.