Protein Alignment eEFSec and Eif2s3y

DIOPT Version :9

• Sequence 1: NP_611584.1
• Gene: eEFSec / 37444
• FlyBaseID: FBgn0034627
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_036141.1
• Gene: Eif2s3y / 26908
• MGIID: 1349430
• Length: 472
• Species: Mus musculus
• Alignment Length: 521
• Identity: 119/521 - (22%)
• Similarity: 200/521 - (38%)
• Gaps: 183/521 - (35%)

  Fly     6 NIGLLGHVDSGKTTLAKALSSISSTAAFDKNPQSVERGITLDLGFSGLLV--------------- 55
            |||.:|||..||:|:.||:|.: .|..| ||  .:||.||:.||::...:
Mouse    43 NIGTIGHVAHGKSTVVKAISGV-HTVRF-KN--ELERNITIKLGYANAKIYKLDDSSCPRPECYR 103

  Fly    56 --------DAPAHLPQGEQLQF------TFVDCPGHASLIRTIIGGAQIIDLMLLVVDAQKG-KQ 105
                    :.|:.:| |.:..|      :|||||||..|:.|::.||.::|..||::...:. .|
Mouse   104 SCGSSTPDEFPSDIP-GTKGNFRLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQ 167

  Fly   106 TQTAECLIIGELLQKKLIVVI-NKIDVYPENQRASKLEKLRLRLAKTLEATTFGGQVPICAVSAL 169
            .||:|.|...|:::.|.|::: ||||:..|:|...:.|::   || .::.|...| .||..:||.
Mouse   168 PQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQI---LA-FVQGTVAEG-APIIPISAQ 227

  Fly   170 QGTHIAELREVLREAYFQPQRNLADPLFMYVDHCFGIKG--------QGTVCTGTLLQGKVQVNN 226
            ...:|..:.|.:.:....|.|:......:.|...|.:..        :|.|..|::|:|.::|..
Mouse   228 LKYNIEVVCEYIVKKIPVPLRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQ 292

  Fly   227 VIELPALGEQRKVKSIQMFRKNVTSASMGDRIGLCVTQFNAKLLERGIITQPGYLKPIYAVCLQF 291
            .||                                        :..||:::.|..|      |..
Mouse   293 EIE----------------------------------------VRPGIVSKDGEGK------LMC 311

  Fly   292 KPIRYYKEVIKSMRKMHISVGHNTVMANVTLFRDTDGTTSTFQLDKEYEYMEDVQPAEVQHNDVI 356
            |||  :.::                   |:||                          .:|||:.
Mouse   312 KPI--FSKI-------------------VSLF--------------------------AEHNDLQ 329

  Fly   357 YALLQFESPVLSPPHSTLIASKLDMDVHSTSCR--------LAFWG---RIAWQTHSSKYFQEEL 410
            ||         :|.....:.:|:|    .|.||        |...|   .|..:...|.:....|
Mouse   330 YA---------APGGLIGVGTKID----PTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRL 381

  Fly   411 PKLRIFKRKQKVGSIQRVVNSSEVIVQNLFKDAKRDLYVGKNVELSTGEKGRIERTFGQTSKVAI 475
            ..:|. :..:|...:|: ::.:||::.|          :|   .||||  ||:........|:.:
Mouse   382 LGVRT-EGDKKAAKVQK-LSKNEVLMVN----------IG---SLSTG--GRVSAVKADLGKIVL 429

  Fly   476 T 476
            |
Mouse   430 T 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eEFSec	NP_611584.1	SelB_euk	5..192	CDD:206676	67/216 (31%)
		SelB	6..467	CDD:225815	117/510 (23%)
		SelB_II	196..278	CDD:293897	12/89 (13%)
		eSelB_III	283..396	CDD:294009	20/123 (16%)
Eif2s3y	NP_036141.1	PTZ00327	13..466	CDD:240362	119/521 (23%)
		eIF2_gamma	42..248	CDD:206675	66/214 (31%)
		G1. /evidence=ECO:0000255|PROSITE-ProRule:PRU01059	48..55		4/6 (67%)
		G2. /evidence=ECO:0000255|PROSITE-ProRule:PRU01059	76..80		2/3 (67%)
		G3. /evidence=ECO:0000255|PROSITE-ProRule:PRU01059	134..137		2/2 (100%)
		G4. /evidence=ECO:0000255|PROSITE-ProRule:PRU01059	190..193		2/2 (100%)
		G5. /evidence=ECO:0000255|PROSITE-ProRule:PRU01059	225..227		1/1 (100%)
		eIF2_gamma_II	249..362	CDD:293889	33/218 (15%)
		eIF2_gamma_III	365..459	CDD:294011	18/83 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3276
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810