Protein Alignment bisc and TM2D1

DIOPT Version :10

• Sequence 1: NP_001356967.1
• Gene: bisc / 37443
• FlyBaseID: FBgn0034626
• Length: 203
• Species: Drosophila melanogaster
• Sequence 2: XP_047287699.1
• Gene: TM2D1 / 83941
• HGNCID: 24142
• Length: 277
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 67/199 - (33%)
• Similarity: 90/199 - (45%)
• Gaps: 48/199 - (24%)

  Fly    22 DCNELQM----MGQFMC---------------PDPARGQIDPKTQQLAGCTREGRARVWCIAANE 67
            |.:.||.    ..||.|               |||   :|:..||:...||.. .|.|.|..|..
Human    82 DLSSLQPPPPGFSQFSCLSLLSSWDYRHAPPHPDP---KINDATQEPVNCTNY-TAHVSCFPAPN 142

  Fly    68 INCTE-TGNAT--------FTREVPCKWTNGYHLDTTLLLSVFLGMFGVDRFYLGYPGIGLLKFC 123
            |.|.: :||.|        |.:.:.|:..|||.....:.||:|||..|.||||||||.:||||||
Human   143 ITCKDSSGNETHFTGNEVGFFKPISCRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFC 207

  Fly   124 TLGGMFLGQLIDIVLIALQVVGPA-----DGSAYVIPYYGAGIHIVRSDNTTYRLPRDDWXWLRQ 183
            |:|...:|.|||.:||::|..|.|     :.|..:|.:  ..:..:.|:|    ||..     ..
Human   208 TVGFCGIGSLIDFILISMQRQGLALLPRLECSGVIITH--CSLEFLGSNN----LPAS-----AS 261

  Fly   184 HSAW 187
            |..|
Human   262 HPVW 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bisc	NP_001356967.1	TM2	94..137	CDD:428337	26/42 (62%)
TM2D1	XP_047287699.1	TM2	172..221	CDD:428337	29/48 (60%)