DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17974 and PRY3

DIOPT Version :9

Sequence 1:	NP_611582.1	Gene:	CG17974 / 37441	FlyBaseID:	FBgn0034624	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_012457.1	Gene:	PRY3 / 853367	SGDID:	S000003614	Length:	881	Species:	Saccharomyces cerevisiae

Alignment Length:	172	Identity:	38/172 - (22%)
Similarity:	56/172 - (32%)	Gaps:	56/172 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 QVDVSRHKADFLHAHNKRRNFLALGKVPGYYPAARMATMVWDDELQYLSMLNTRTCKLDHDDCHN 120
            |......::|.|:.|||   |.||        ....|.:.|.|.|...:....     |..||..
Yeast    19 QTTFPNFESDVLNEHNK---FRAL--------HVDTAPLTWSDTLATYAQNYA-----DQYDCSG 67

  Fly   121 TYRYANS--GQNLCAVWRPRSPHVNVTSLVEECLGLWFNEFDLIDSSFIDSFKVTPIF-EDYGHF 182
            ...:::.  |:||...:..       |..|:    .|:.|....:.|       .|.| |..|||
Yeast    68 VLTHSDGPYGENLALGYTD-------TGAVD----AWYGEISKYNYS-------NPGFSESTGHF 114

  Fly   183 AELSVDKNFAVGCSIMRFTRPDYPSVYIY------NFI-CNY 217
            .::.......:||.            |.|      |:| |:|
Yeast   115 TQVVWKSTAEIGCG------------YKYCGTTWNNYIVCSY 144

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17974	NP_611582.1	SCP_euk	63..218	CDD:240180	37/165 (22%)
PRY3	NP_012457.1	CAP_PRY1-like	24..152	CDD:349403	37/167 (22%)
PRY3	NP_012457.1	ser_rich_anae_1	<598..>855	CDD:411418
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344579
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830