DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17974 and PI16

DIOPT Version :9

Sequence 1:	NP_611582.1	Gene:	CG17974 / 37441	FlyBaseID:	FBgn0034624	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_001186088.1	Gene:	PI16 / 221476	HGNCID:	21245	Length:	463	Species:	Homo sapiens

Alignment Length:	182	Identity:	39/182 - (21%)
Similarity:	56/182 - (30%)	Gaps:	55/182 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 AARMATMVWDDELQYLSMLNTRTCKLDHDDCHNTYRYANSGQNLCAV-------------WRPRS 139
            |:.|..|.||:||...:....|.|...    ||..| ...|:||.|:             |....
Human    51 ASDMLHMRWDEELAAFAKAYARQCVWG----HNKER-GRRGENLFAITDEGMDVPLAMEEWHHER 110

  Fly   140 PHVNVTSLV----EECLGLWFNEFDLIDSSFIDSFKVTPIFEDYGHFAELSVDKNFAVGCSIMRF 200
            .|.|:::..    :.|                            ||:.::...|...:||. ..|
Human   111 EHYNLSAATCSPGQMC----------------------------GHYTQVVWAKTERIGCG-SHF 146

  Fly   201 TR--PDYPSVYIYNFICNYASL-YALGAPVYETGRAASRCTTGKSHFYPGLC 249
            ..  .......|...:|||... ...|...|:.|...|:|.:| .|....||
Human   147 CEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEGTPCSQCPSG-YHCKNSLC 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17974	NP_611582.1	SCP_euk	63..218	CDD:240180	29/148 (20%)
PI16	NP_001186088.1	SCP_HrTT-1	33..166	CDD:240186	29/148 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..281
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	383..408
		O-glycosylated at one site	386..395
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920