DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17974 and vap-1

DIOPT Version :9

Sequence 1:	NP_611582.1	Gene:	CG17974 / 37441	FlyBaseID:	FBgn0034624	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	NP_001024553.1	Gene:	vap-1 / 181768	WormBaseID:	WBGene00006886	Length:	424	Species:	Caenorhabditis elegans

Alignment Length:	243	Identity:	59/243 - (24%)
Similarity:	86/243 - (35%)	Gaps:	40/243 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SWCDPDLCGNGVRHIACRTTGNFHRRCQPDAVQVDVSRHKADFLHAHNKRRNFLALGKVPGYYPA 88
            |.|...||....:.....|    ...|.....|.|.:|.  :||..|||.|..||.|.......|
Worm   203 SQCKNGLCYKAPQAPVVET----FTMCPSVTDQSDQARQ--NFLDTHNKLRTSLAKGLEADGIAA 261

  Fly    89 ARMATMVWD-DELQYLSML--NTRT----CKLDHDDCHNTYRYANSGQNLCAVWRPRSPHVNVTS 146
            ...|.|... .:|:|...:  |.||    |...|.   .:.:....|:||..:.....|.:..
Worm   262 GAFAPMAKQMPKLKYSCTVEANARTWAKGCLYQHS---TSAQRPGLGENLYMISINNMPKIQT-- 321

  Fly   147 LVEECLGLWFNEF-DLIDSSFIDSFKVTPIFE-DYGHFAELSVDKNFAVGCSIMRFTRPDYPSVY 209
             .|:....|::|. |....|  |:.....:|: ..||:.:::.:....:||.:.......| ||.
Worm   322 -AEDSSKAWWSELKDFGVGS--DNILTQAVFDRGVGHYTQMAWEGTTEIGCFVENCPTFTY-SVC 382

  Fly   210 IYNFICNYAS--LYALGAPVYETGRAASRCTTGKSHFYPG--LCSTRE 253
            .|....||.:  :|..|:|          ||....  .||  .||..|
Worm   383 QYGPAGNYMNQLIYTKGSP----------CTADAD--CPGTQTCSVAE 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17974	NP_611582.1	SCP_euk	63..218	CDD:240180	39/163 (24%)
vap-1	NP_001024553.1	SCP	31..175	CDD:214553
vap-1	NP_001024553.1	SCP	234..386	CDD:214553	39/162 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020