DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17974 and crispld2

DIOPT Version :9

Sequence 1:	NP_611582.1	Gene:	CG17974 / 37441	FlyBaseID:	FBgn0034624	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	XP_003199065.1	Gene:	crispld2 / 100535149	ZFINID:	ZDB-GENE-130131-1	Length:	508	Species:	Danio rerio

Alignment Length:	236	Identity:	59/236 - (25%)
Similarity:	96/236 - (40%)	Gaps:	56/236 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 FHRRCQPDAVQVD--VSRHKA-------DFLHAHNKRRNFLALGKVPGYYP-AARMATMVWDDEL 100
            :....:|::.:.|  |...:|       :.|..|||.|     |:|   || |:.|..|:|||||
Zfish    35 YQEELEPNSTKPDAPVRTRRAIEWSDREEILKLHNKLR-----GEV---YPTASNMEYMIWDDEL 91

  Fly   101 QYLSMLNTRTCKLDH--DDCHNTYRYANSGQNLCAVW-RPRSPHVNVTSLVEECLGLWFNEFDLI 162
            :..:......|:.:|  .|.     ..:.||||...| |.|||..:|.:        |::|  :.
Zfish    92 ERSATSWAEQCQWEHGPQDL-----LMSIGQNLAVHWGRYRSPAYHVQA--------WYDE--VK 141

  Fly   163 DSSFIDSFKVTPIFED------YGHFAELSVDKNFAVGCSIMRFTRPDY------PSVYIYNFIC 215
            |.::....:..|...:      ..|:.:|.......|||::....|.:.      .:||:   :|
Zfish   142 DYTYPYPHECNPWCPERCSGPMCTHYTQLVWATTNRVGCAVHVCPRMNVWGEIWENAVYL---VC 203

  Fly   216 NYASL-YALGAPVYETGRAASRCTTGKSHFYPGLCSTREVY 255
            ||:.. ..:|...|:.||..|:|...    |.|:|.....|
Zfish   204 NYSPKGNWIGEAPYQHGRPCSQCPPS----YGGVCRDNLCY 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17974	NP_611582.1	SCP_euk	63..218	CDD:240180	45/177 (25%)
crispld2	XP_003199065.1	SCP_euk	61..206	CDD:240180	44/170 (26%)
		LCCL	299..382	CDD:128866
		LCCL	402..495	CDD:281766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585814
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850