DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9822 and PRY3

DIOPT Version :9

Sequence 1:	NP_611581.1	Gene:	CG9822 / 37440	FlyBaseID:	FBgn0034623	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_012457.1	Gene:	PRY3 / 853367	SGDID:	S000003614	Length:	881	Species:	Saccharomyces cerevisiae

Alignment Length:	209	Identity:	43/209 - (20%)
Similarity:	70/209 - (33%)	Gaps:	63/209 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 IVNEHNKRRNYIASGSLPGYYPATRMATMVWDEELEYLATLNLKTCYLEHDDC-----HNSYRFR 126
            ::|||||.|.....           .|.:.|.:.|...|     ..|.:..||     |:...:
Yeast    29 VLNEHNKFRALHVD-----------TAPLTWSDTLATYA-----QNYADQYDCSGVLTHSDGPY- 76

  Fly   127 NLGQNLCGVDRRRNWDLNVTNLVEQSMGLWFGEHKLIDSSYITDFKLTKD--LEKYGHFVETVLD 189
              |:||.         |..|:  ..::..|:||        |:.:..:..  .|..|||.:.|..
Yeast    77 --GENLA---------LGYTD--TGAVDAWYGE--------ISKYNYSNPGFSESTGHFTQVVWK 120

  Fly   190 RNTHVGCAMMRFTNPQYPFL------YI---YNTACNYASVYAIGV-PVYNAGKPASECRTGSNP 244
            ....:||.        |.:.      ||   ||...||...:|..| |:.:....:|...:.::.
Yeast   121 STAEIGCG--------YKYCGTTWNNYIVCSYNPPGNYLGEFAEEVEPLISTVSSSSSSSSSTST 177

  Fly   245 EYPALCSIKEQYNP 258
            ....:.:|.....|
Yeast   178 TSDTVSTISSSIMP 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9822	NP_611581.1	SCP_euk	64..219	CDD:240180	36/167 (22%)
PRY3	NP_012457.1	CAP_PRY1-like	24..152	CDD:349403	37/168 (22%)
PRY3	NP_012457.1	ser_rich_anae_1	<598..>855	CDD:411418
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344575
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830