DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9822 and CRISPLD2

DIOPT Version :9

Sequence 1:	NP_611581.1	Gene:	CG9822 / 37440	FlyBaseID:	FBgn0034623	Length:	263	Species:	Drosophila melanogaster
Sequence 2:	NP_113664.1	Gene:	CRISPLD2 / 83716	HGNCID:	25248	Length:	497	Species:	Homo sapiens

Alignment Length:	266	Identity:	64/266 - (24%)
Similarity:	94/266 - (35%)	Gaps:	73/266 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PDNTVHIACNNDGKFHESCSPDATMVD--LKPY---------RKLIVNE--------HNKRRNYI 78
            |...:.:.|.:.|..    .|:.|:::  |..|         |:.|..|        |||.|..:
Human    10 PLGLLFLVCGSQGYL----LPNVTLLEELLSKYQHNESHSRVRRAIPREDKEEILMLHNKLRGQV 70

  Fly    79 ASGSLPGYYPATRMATMVWDEELEYLATLNLKTCYLEHDDCHNSYRFRNLGQNLCGV--DRRRNW 141
            ..       .|:.|..|.||:|||..|......|..||..   :....::|||| |.  .|.|:.
Human    71 QP-------QASNMEYMTWDDELEKSAAAWASQCIWEHGP---TSLLVSIGQNL-GAHWGRYRSP 124

  Fly   142 DLNVTNLVEQSMGLWFGEHKLIDSSYITDFKLTKDLEKYG----HFVETVLDRNTHVGCAMMR-- 200
            ..:|.:        |:.|.|.....|.::..........|    |:.:.|......:|||:..
Human   125 GFHVQS--------WYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCR 181

  Fly   201 --------FTNPQYPFLYIYNTACNYASVYAIGVPVYNAGKPASECRTGSNPEYPA-----LCSI 252
                    :.|..| |:..|:...|:     ||...|..|:|.|||    .|.|..     ||..
Human   182 KMTVWGEVWENAVY-FVCNYSPKGNW-----IGEAPYKNGRPCSEC----PPSYGGSCRNNLCYR 236

  Fly   253 KEQYNP 258
            :|.|.|
Human   237 EETYTP 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9822	NP_611581.1	SCP_euk	64..219	CDD:240180	42/178 (24%)
CRISPLD2	NP_113664.1	SCP_euk	56..201	CDD:240180	37/164 (23%)
		LCCL	286..370	CDD:128866
		LCCL	387..479	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151215
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850